This is a meta study of 10 studies which did find a decline in IQ
Previous systematic reviews and meta-analyses of cross-sectional data assessing the effect of cannabis on cognitive functioning and intelligence show inconsistent results. We hypothesized that frequent and dependent cannabis use in youth would be ...
pmc.ncbi.nlm.nih.gov
Full-scale IQ decline
We found a significant overall effect for the association between frequent or dependent cannabis use and IQ change [Cohen's
d = −0.132, (95% CI −0.198 to −0.066)
p < 0.001]. This corresponds to a 1.98-point decline in IQ (95% CI 0.99–2.97). The
I2 test for heterogeneity was 0.2% indicating low between study statistical heterogeneity.
In terms of our exploratory analysis, we extracted verbal IQ change effect sizes from four available studies (see online Supplementary eTable 4 for individual study effect sizes). The pooled effect size of verbal IQ decline was
d = −0.196 CI (−0.27 to −0.122)
p < 0.001). This was a homogenous finding,
I2 = 0. This corresponds to a decline of 2.94 verbal IQ points CI (1.83–4.05). There was no evidence of performance IQ change following frequent or dependent cannabis use. Estimates of effect sizes were available for five studies (see online Supplementary eTable 5 for individual study effect sizes). The pooled effect size was −0.004 CI = (−0.087–0.080),
p = 0.938. There was no evidence of heterogeneity in this finding,
I2 = 0. For both verbal and performance IQ change findings, all estimates were within the pseudo 95% confidence intervals within funnel plots, there was no evidence of publication bias from results of the weight-function model and results were not driven by a single study from leave one out sensitivity analysis. See
Figure 1, online Supplementary eFigure 6–7; online Supplementary eTable 10–11 for forest plots, funnel plots and leave one out sensitivity analysis tables, respectively.