The agency says it soon will withdraw approval for any of those medications containing more than 325 mg of acetaminophen. It also said that it is planning new regulatory action on over-the-counter acetaminophen, but did not give details.
Nowhere does there seem to be any mention of any new research that would lead anyone to believe that it's more dangerous than previously thought. I also have a big problem with their saying "no additional benefit that outweighs the added risks ." What makes them the arbiters of what outweighs what?
FDA warns against high-dose prescription acetaminophen
There are actually many hundreds of studies that show how dangerous acetaminophen is. Overdoses of acetaminophen are the leading cause of liver failure in the United States, with more than 70,000 people ending up in the Emergency room each year from accidental overdoses.
Feel free to disregard their suggestions, but keep that poison control number handy.