To paraphrase from the Hadith, one of Muhammad's last instructions;
"I have been commanded by Allah to fight all of mankind until all of mankind has embraced Islam."
A study of the Koran/Qur'an, Hadith, and Sira reveal that Islam believes that Paradise/Heaven is of many levels. A peaceful and non-violent Muslim only attains the lowest level(basement so to speak). To attain higher levels and greater rewards depends on being a holy warrior (mudjadeen) and engaging in Holy War/Jihad. More successful at such the higher the level and rewards in Paradise/Heaven.
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WikiIslam portal for articles about Islamic Scriptures
www.wikiislam.net
This would suggest that Islam is a prescription for perpetual conflict/war and one of reasonable intelligence should be concerned about what this means for everyone here on Earth. Islamophobic is comparable to being Naziphobic.
Largest amount of genocide against the Native Americans occurred with initial explorations and colonizations by Spanish and Portuguese in the 16th and 17th centuries.
It was the near 90% decline of that indigenous population that hand those two nations start the process of import of slaves, mostly from Africa.
Many of those "pioneers" were first generation immigrants from parts of Europe whom came to the USA and disregarded Federal treaties with the Native Americans.