I saw a documentary on Netflix of a fire woman in WV who drives around and helps those in need. Those they help all have chemical addictions of numerous kinds. This show focused on those who help others with these addictions and there were some tear jerking moments. Many of these people just regular, blue collar folks who became caught up in it and are trying to come clean, others who died due to their demons.
Here is something that might surprise many, but it shouldn't if one understands history, many of these synthetic drugs are coming from China. Don't be surprised if there is a concerted effort by certain foreign governments to poison Americans, of course; it will be culpable deniability, their authorities will simply look the other way. The British did it to the Chinese over a century ago, which is why they held HK for so long. Canadian police have been reaching out to the Chinese about these shipments, and I am willing to bet there is something far more nefarious behind this.
I bet if you asked the FBI about these issues they could offer some far more startling details than I could. America has to be weary of the enemies of the state who operate from afar.