It may turn out that you are trapped and there is nowhere to run
Then it goes right back to what was said about "situational awareness", and never let yourself get into that situation in the first place.
Look, 14 years ago I was jumped by 2 guys with metal pipes and the only thing I had in my hand was 2 pizzas. They thought they had set up the perfect ambush. Want to know what I did?
Yep, I ran.
Only a fool lets themselves get into a situation where they have no means of escape. And a bigger fool lets himself get into a fight with somebody with a knife.
Most of you all on the "knife" side of this are wanting to play some kind of macho Rambo fantasy. I could not give a damn about your fantasy. And want to know something? I am much less worried about them throwing their knife. Even less know how to throw one than know how to fight with one. And odds are they just threw their weapon away. As I am still leaving.