The city, which is the second-largest city in the country, was told the new move was 'necessary for the protection of life and property in the City of Los Angeles'.
Garcetti urged residents to 'cancel everything,' saying no one should be hosting gatherings or going to gatherings. Those who break the rules may potentially be arrested, he warned.
It comes as Los Angeles County, which is home to the city and has about 10 million residents total, reported surges in daily cases with 6,000 infections recorded yesterday.
Garcetti's order limits nearly all social gatherings of people from more than a single household but exempts religious services and protests protected by the constitution.
He also directed businesses requiring the presence of workers to close, and set restrictions on travel, but specified a long list of exceptions to both.
The city was told the new move was 'necessary for the protection of life and property'. It comes hours after mayor Eric Garcetti told the almost four million people in rthe city limits to 'cancel everything'.
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The "Progressive" sheep will docilely march to their rooms and cower.