Mr Kerry, who is set to visit Kiev on Tuesday to meet the new leadership, warned Russia on Sunday that it risked exclusion from the Group of Eight nations and faced possible sanctions for sending troops into Ukraine's southern Crimea region.
In a statement on its website Russia's foreign ministry said:
"We consider the threats against Russia made in a series of public statements by US Secretary of State John Kerry over the latest events in Ukraine and in Crimea to be unacceptable,"
Moscow accused Kerry of relying on "Cold War cliches", saying that he had not bothered to understand the complex processes taking place in Ukrainian society.
Kerry failed to "objectively assess the situation that is continuing to deteriorate after the forcible seizure of power in Kiev by radical extremists," the ministry said.
It accused the United States and its allies of turning a blind eye to the "rampant Russophobia and anti-Semitism" of the opposition protesters who took power in Kiev.
"The West's allies now are outright neo-Nazis who wreck Orthodox churches and synagogues," the ministry said.
Ukraine live - Telegraph