'An hour later, it has happened! I am jubilant; Bart looks stunned. He knows he is beginning to read. All the wonderful world of books is within his grasp. He looks at me with a level gaze and asks, "How did I do that? What did I do?" He is, of course, quite right in saying that he did something, not that I did it. My answer is inadequate: "I don't know. I wish I did. I think I can help you do some more of whatever that was that you did." At that, Bart gives me a look of pure delight and trust, and the hairs on my arm stand up.
I really don't know what happened. But I was there when the glory happened, and I shall never be quite the same. I shall remain in debt to Bart, and I shall continue to search. That is it; I am still searching. That is what this book is all about.'
(Anita Griffiths, Teaching the Dyslexic Child)
To render the saxophone a complete alphabet typewriter, problematic letters are:
U (selenocysteine, 21st amino acid as a vowel)
O (pyrrolysine, 22nd amino acid as a vowel)
B
J
X
Z
There are seemingly no efficient parameters by which to assign isoelectric points to selenocysteine and pyrrolysine, thus placing them in sequence to the others (post #2). Nonetheless, two trajectories are,
2018 Isoelectric Focusing of Selenocysteine
Detection of Selenoproteins by Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP MS) in Immobilized pH Gradient (IPG) Strips. - PubMed - NCBI
Jul 2019 Pyrrolysine
Anticipating alien cells with alternative genetic codes: away from the alanine world! - PubMed - NCBI