I believe it is about Paul's encounter with Jesus Christ and his subsequent conversion, Drifter. As to the second part of your question - We know that in Isaiah Chapter 17 Isaiah prophesies of the destruction of Damascus. I do not believe that has any significance or relationship to the story of Paul and is a separate matter.
On the subject of Assyria (modern day Syria) God makes clear that in the last days He will use the Assyrians as a rod of correction to a hypocritical nation - but as you can see in Isaiah 17 judgment shall also fall on the Assyrians (later).
Looking up King James Version Isaiah Chapter 10 - hang on..........
here it is:
http://bibletruthpublishers.com/isaiah-10/king-james-version/lbc689KJV
Isaiah 10 (KJV)
1
Woe unto them that decree unrighteous decrees, and that write grievousness which they have prescribed;
2
To turn aside the needy from judgment, and to take away the right from the poor of my people, that widows may be their prey, and that they may rob the fatherless!
3
And what will ye do in the day of visitation, and in the desolation which shall come from far? to whom will ye flee for help? and where will ye leave your glory?
4
Without me they shall bow down under the prisoners, and they shall fall under the slain. For all this his anger is not turned away, but his hand is stretched out still.
5
O Assyrian, the rod of mine anger, and the staff in their hand is mine indignation.
6
I will send him against an hypocritical nation, and against the people of my wrath will I give him a charge, to take the spoil, and to take the prey, and to tread them down like the mire of the streets.
7
Howbeit he meaneth not so, neither doth his heart think so; but it is in his heart to destroy and cut off nations not a few.
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For those who do not believe that God will use the unbelievers to judge his own people / nations who have backslid, there is precedent for it in the book of Habakkuk and also if you read Psalm 17:13 you'll see who God's sword is. God holds his own people to a higher standard. Which is why America is under the judgment of God right now. It is no coincidence the Assyrians are the ones coming through the gates of the city now. Still, I believe that the prayers of righteous men (and women) availeth much.