In my 45 year public and mainly private sector career, I saw a score of mass layoffs including my own on a few occasions. Rarely was anyone missed after they were gone, personally or functionally. My 5 years as a civilian DoD employee were spent in an agency (DLA) that could have been entirely removed with little impact on DoD's operations.
The 1,300 or so State Department employees who got their pink slips yesterday were, statistically speaking, 90% voting Democrats, and I doubt that any of their functions was important to the country.
It would be very interesting to follow their career paths and see how many of them actually are forced to get real jobs to support themselves - jobs in private industry where they are "at-will" employees and can be removed again if they are not productive. Frankly, I rather doubt it. They will go to work for other government agencies, non-profits, NGO's and such, maybe do something equally worthless for a state or local government.
But it would be interesting to know.