As a start, I would cut:
Department of Uneducation - 50% (Return the funds to states and Commonwealths (there are four Commonwealths) to go directly to upgrading school facilities to meet technology advancements.)
Department of Labor -30%
Department of Commerce - 30%
Combine the two previously referenced departments into one
EPA - 50%
Department of Unjustice - 30%
Homeland InSecurity - 30% (Especially in the administrative area.)
Consumer Financial Board - 50% (Have you seen how much money they spent on n designer furniture)
Every single cut could be accomplished by a freezing on all new hiring, elimination of the abysmally high number of 'Under Secretaries and Assistant Secretaries positions (all of which do little but sit in large offices writing documents on matters they have no knowledge of)
DOD - A requirement that ALL programs be reviewed and any overlap be combined into one updated grouping, with a corresponding reduction in funding. A reduction in civilian DOD employees and utilization of active duty personnel to fill some of the civilian positions.
A comprehensive review of all government programs. Where more then one agency is part of a program, ex. school lunch programs (four agencies are involved), the programs be combined within one agency and personnel be cut.
This is only an initial list.
Oh, as a thought to resolution to the continuing VA ineptitude, all new hires at the VA, in management, must be former high ranking NCOs such as Sgt. majors, etc. As to physicians for basic health checkups, testing, etc., utilize senior level residents from nearby medical schools. In prior years, a VA hospital in VA followed such a practice.