Vaccinations target only the spike, so the non-spike mutations now being added and that are being fear-mongered for Omicron/Nu are not applicable to vaccine arguments until the virus is inside the host, and the viral loads on the surface of mouths, throats, nasal passages, are also not applicable to vaccine arguments. Those viral loads are the same in both vaxxed and unvaxxed.We do not know the actual the transmission rate of the omicron variant, nor do we know how effective the the various vaccines will be against it. It will be 3 or 4 weeks before we know the transmission rate and bout 2 weeks before we know how effective our vaccines will be against this new variant.
Keep in mind that the mu variant was reported a few months ago in South America and created much anxiety. The transmission rate was estimated to be very high. As it turned out the transmission rate was much less than the delta variant and it was no longer considered a variant of interest even though vaccines were slightly less effective against it.
The coronavirus mutates more than most viruses so we will be seeing many mutations of interest. Since every time the the virus replicates which has to be at least trillions of times a second, there is an opportunity for mutation. Most of those mutation are no interest but occasion one occurs that is a potential threat. The only way to reduce mutations is to reduce replications and the only what to do that is through vaccinations, masks, and social distancing.