Ivermectin works for Covid and Per reviewed study from Peru proves it

[badger2]

Foamy viruses are a subgenus of retroviruses. The Melbourne ivermectin study used African Green Monkey/humanSLAM cells. McKernan being censored (post #194) because he was getting too close when mentioning ancient retroviruses links to Worobey's two publications on ancient coelacanth viruses and a third by Indian authors:

(2012) Worobey / Coelacanth

An endogenous foamy-like viral element in the coelacanth genome - PubMed

Little is known about the origin and long-term evolutionary mode of retroviruses. Retroviruses can integrate into their hosts' genomes, providing a molecular fossil record for studying their deep history. Here we report the discovery of an endogenous foamy virus-like element, which we designate...

pubmed.ncbi.nlm.nih.gov

(2016) Worobey / Coelacanth

Foamy-like endogenous retroviruses are extensive and abundant in teleosts - PubMed

Recent discoveries indicate that the foamy virus (FV) (<i>Spumavirus</i>) ancestor may have been among the first retroviruses to appear during the evolution of vertebrates, demonstrated by foamy endogenous retroviruses present within deeply divergent hosts including mammals, coelacanth, and...

pubmed.ncbi.nlm.nih.gov

India / HIV-1 Inhibition by Coelacanth SERINC2

Coelacanth SERINC2 Inhibits HIV-1 Infectivity and Is Counteracted by Envelope Glycoprotein from Foamy Virus - PubMed

<span><i>SERINC5</i> restricts nef-defective HIV-1 by affecting early steps of the virus life cycle. Distantly related retroviruses with a wide host range encode virulent factors in response to challenge by <i>SERINC5</i>. However, the evolutionary origins of this antiretroviral activity, its...

pubmed.ncbi.nlm.nih.gov

Proof that there is a foamy virus of African Green monkeys:
AGM Simian Foamy Virus Type 3

UniProt

uniprot.org

 

[badger2]

Ivermectin Worked: New Peer-Reviewed Study Proves It - 🔔 The Liberty Daily

A preprint paper showing ivermectin’s effectiveness against COVID-19 in Peru convinced a group of doctors that widespread ivermectin distribution could end the pandemic in October 2020 Because the paper wasn’t yet peer-reviewed, it was brushed off; ivermectin for COVID-19 was vilified, as were...

thelibertydaily.com

Once again Fauci put profits over people like he did in the 80s with AZT. Wonder if the media will still call it horse paste?

'In Argentina, in the summer of 2020, Dr. Hector Carvallo conducted a randomized placebo-controlled trial of ivermectin as a preventative, finding 100 percent efficacy against COVID. Carvallo's team found no infections among the 788 workers who took weekly ivermectin prophylaxi, whereas 58 percent of the 407 controls had become ill with COVID-19.

A later observation from Bangladesh -- also investigating ivermectin as a pre-exposure prophylaxis against COVID-19 among health care workers -- found nearly as spectacular results: only four of the 58 volunteers who took minimal dose of ivermectin (12 mcg once per month for four months) developed mild COVID-19 symptoms, compared to 44 of the 60 health care workers who had declined the medication.'
(RFK Jr., The Real Anthony Fauci)

Selamectin, a variant of IVM, has been used for scabies in the proven SARS1 vector, Paguma larvata.

RFK Jr. continues: The Annals of Dermatology and Venereology reported that in a French nursing home, all 69 residents - average age 90 - and 52 staff survived a COVID-19 outbreak. As it turns out, they had all taken ivermectin for scabies infestation. COVID decimated the surrounding community, but only seven elder home residents and four staff were affected, and all had mild illness. None required oxygen of hospitalization.'

 

[Delldude]

But the doctors say pharmacies stopped filling their prescriptions for the drug — which the FDA approved in 1996 for human use to treat parasitic diseases caused by round worms and black flies — after the FDA launched a public relations campaign in spring 2021 sounding the alarm that people were being hospitalized after self-medicating with large doses of the drug intended for deworming livestock that they had purchased over the counter.

If people were self medicating they were not doing so with a doctors approval.

 

[badger2]

E.C. Holmes is mentioned above, second human to receive the published SARS2 genome. Holmes was lead author of the origins paper. Holmes's maps of the Wuhan seafood market are faulty, as Edward Hooper explains here:

COVID-19 Origins

https://aidsorigins.com/covid-19-origins-if-it-was-a-lab-leak-was-it-caused-by-biowarfare-research/

 

[badger2]

aidsorigins.com/covid-19-origins-if-it-was-a-lab-leak-was-it-caused-by-biowarfare-research/

 

[badger2]

The URL will function if typed into the spacebar.

 

[badger2]

Based on this Melbourne study above, RFK Jr. dates the Peruvian response to 8 May 2020:

'....on 8 May 2020 perus -- then under siege by a crushing COVID endemic -- adopted ivermectin in its national guidelines. "Peruvian doctors already knew the medicine, widely prescribed it for parasites, and health authorities knew it was safe and were comfortable with it," recalls Dr. Pierre Kory. COVID deaths dropped precipitously -- by 14-fold -- in the regions where the Peruvian government effectively distributed ivermectin. Reductions in deaths correlated with the extent of IVM distributions in all 25 states.

In December 2020, Peru's new president, under pressure from WHO, severely restricted IVM availability and COVID cases rebounded with deaths increasing 13-fold. In prophylaxis studies, ivermectin repeatedly demonstrated far greater efficacy against COVID than vaccines at a fraction of the cost.'

 

[badger2]

The NEJM article on the Brazil trial in post #188 used 400 micrograms ivermectin per kilogram body weight once daily for three days. (The dose used in the Melbourne study was 5 microM).

The Brazil patients were all SARS-2 positive and were chosen who had symptoms for up to 7 days. This would have already allowed much nuclear integration of the virus so that ivermectin's action against the protein SARS2 uses for nuclear import (importin alpha/beta) would be after the fact. This is a good way to sabotage the trial from the beginning, because ivermectin physically attaches to importin.

 

[eagle1462010]

there's no hearsay here or it's my word ... its total factual information that Ivermectin does nothing for covid 19 ...RFK hasn't any citation that is credible... RFK has become the family idiot ... that they are all ashamed of ... His sources are fake ...his citations are fake ... everything about RFK jr. is fake ...get it moron stop using him as if he has value because he's a Kenedy ... he's using his name to sound important ... he's mentally deranged ... nobody in his entire family agrees with him at all on anything he says ...nobody in the democratic party accepts his citations as being credible ... nobody in the medical community accepts his citations ... stop playing with peoples lives with your bullshit post ... people are dying because of you

Ivermectin, an anti-parasitic drug used as the primary ingredient in canine heartworm preventatives, was touted as a “new tool” in the “arsenal” against SARS-CoV-2, the coronavirus strain responsible for the 2020 COVID-19 pandemic. Media publications like far-right cable channel OAN touted the drug as a “cure” that could kill the virus in “just 48 hours.”


Our analysis determined that this claim is a mixture of half-truths combined with misleading and overzealous claims.


Such claims began circulating online in April 2020 when Australian researchers with the Monash Biomedicine Discovery Institute and the Peter Doherty Institute of Infection and Immunity shared findings from an in vitro study that was in preprint and had not yet been peer reviewed by the scientific community. Similar claims made headway again in June, when the research was published in the scientific journal Antiviral Research, concluding that the FDA-approved drug ivermectin — which is most commonly used to treat internal and external animal parasites — was found to effectively stop SARS-CoV-2 virus from replicating in cells cultured in petri dishes. An in vitro study differs from an in vivo study in that the research occurs inside of extracted or grown cells cultured in a lab setting rather than in vivo, whereby the research takes place within a plant, human or animal. In vitro studies typically occur in the very early stages of research as a way to test pharmaceutical drugs or interventions before moving on to living organisms.


However, there is currently little evidence to suggest that ivermectin can “cure” COVID-19 in humans. That’s because throughout the course of the study, the drug was not given to people or animals, and the findings can only provide a potential path of future study into the safety and effectiveness of the drug.


In a separate study published in July 2020 in the Journal of Bangladesh College of Physicians and Surgeons, researchers described treating 100 patients in Bangladesh who tested positive for COVID-19 — an admittedly small sample size — with a combination treatment of ivermectin and doxycycline, along with “supportive treatment.” Nearly three-quarters of the patients were considered to have a “mild” case of the disease while one-in-ten were classified as “moderate,” which begs the question of whether the test subjects improved on their own accord or if it was some form of the various treatments given.


“It is too early in this pandemic to claim major successes of the effectivity of our combination therapy (Ivermectin and Doxycycline) as our number is small and there is no control group,” concluded the study authors. "Nevertheless, the results encourage us to continue the clinical study for people of the world in this improbable crisis as each and every life counts.”


There are studies underway to further determine whether ivermectin may be used in future human trials, though they have neither been peer-reviewed nor published in a reputable journal at the time of writing.


One such study is a U.S. clinical trial that took place between May 31 and July 27, 2020, in which researchers administered a preventative treatment of ivermectin to more than 200 asymptomatic individuals who had come in close contact with a confirmed COVID-19 patient but were not diagnosed with the disease themselves. Patients were measured for their development of COVID-19 symptoms within 14 days and diagnosis was then confirmed via a swab test. The preliminary and small-scale study, which has not been published in a peer-reviewed medical journal, suggested that ivermectin may be used to prevent infection of COVID-19. But again, the findings require further testing and evidence before they may be applied to larger human populations.


In March 2022, more than 3,500 patients diagnosed with symptomatic SARS-CoV-2 were analyzed in Brazil. Of those, 679 patients were randomly assigned to receive ivermectin, 679 a placebo, and the rest were given another medical intervention. Publishing their findings in the peer-reviewed scientific journal The New England Journal of Medicine, researchers concluded that there "were no significant effects of ivermectin use on secondary outcomes or adverse events."


"Treatment with ivermectin did not result in a lower incidence of medical admission to a hospital due to progression of Covid-19 or of prolonged emergency department observation among outpatients with an early diagnosis of Covid-19," wrote the study authors.


Ivermectin is a key ingredient in the canine heartworm preventative Heartguard. The anti-parasitic belongs to a class of medication called anthelmintics and is commonly given to animals via an oral tablet that works by either killing the parasites or stopping them from developing, according to the U.S. National Library of Medicine. Ivermectin is approved by the FDA for human use and is mainly prescribed in its topical form as a treatment for external parasites like head lice. In some cases, ivermectin may be prescribed as an oral tablet, a medication called Stromectol, to treat some parasitic roundworm infections.


Throughout the course of the pandemic, the scientific community rushed to find potential treatments for SARS-CoV-2, a single-stranded RNA virus closely related to SARS-CoV, the coronavirus responsible for the 2003 SARS pandemic. Scientists turned to previous SARS-related research in order to find treatments that may also be effective in treating COVID-19, one of which was ivermectin.


To test whether the anti-parasitic may have a similar effect on SARS-CoV-2, scientists cultured the cells of fetal pigs — again, not humans — in petri dishes in a laboratory setting before infecting the cultured cells with the coronavirus. When ivermectin was administered, it was shown to effectively stop SARS-CoV-2 replicating in these cultured cells. Within 24 hours of infection, there was a 93% reduction in viral replication and a 99.8% reduction by 48 hours. Though results are promising and show potential for the effective use of the drug as an antiviral in COVID-19 and other diseases, there is no clinical evidence to suggest that ivermectin can inhibit the replication of SARS-CoV-2 in humans. In short, it is far too early to claim that ivermectin is an effective cure or a treatment, or that it may become one in the near future.


In April 2020, the U.S. Food and Drug Administration (FDA) announced that such studies are common in the early stages of drug development and warned against self-medication until additional testing occurs. The FDA’s Center for Veterinary Medicine (CVM) issued a public letter following the April prepublication of the paper, expressing the agency’s concern about people who may self-medicate with ivermectin intended for animals. At the time of publication, there was no emergency use authorization for ivermectin in the U.S. to prevent or treat COVID-19, a legal measure that would bypass many regulatory laws.


“This type of study is commonly used in the early stages of drug development. Ivermectin was not given to people or animals in this study," wrote CVM Director Dr. Steven Solomon. "Additional testing is needed to determine whether ivermectin might be safe or effective to prevent or treat coronavirus or COVID-19.”


Solomon also said that the “FDA is concerned people should never take animal drugs, as the FDA has only evaluated their safety and effectiveness in the particular animal species for which they are labeled. These animal drugs can cause serious harm in people. People should not take any form of ivermectin unless it has been prescribed to them by a licensed health care provider and is obtained through a legitimate source.”


The ivermectin study prompted a comprehensive review published in The Journal of Antibiotics analyzing both in vitro and in vivo studies to determine the antiviral effects of ivermectin since 1970. Ivermectin was shown to have antiviral effects on Zika, dengue, yellow fever, and West Nile virus, among others — findings that further highlight that the anti-parasitic drug “could serve as a potential candidate in the treatment of a wide range of viruses including COVID-19.” Even so, the authors warned that clinical trials are still necessary to determine whether the drug is both safe and effective in human patients infected by SARS-CoV-2.


In short, the efficacy of ivermectin in combating COVID-19 depends on further preclinical testing and, if it were to pass, then the drug must undergo a four-part series of clinical trials as required by law. As of August 2020, it was too soon to draw conclusions about the effectiveness of ivermectin as a treatment or cure for COVID-19.

BS

 

[John Edgar Slow Horses]

ivermectin does nothing about Covid 19

 

[John Edgar Slow Horses]

ivermectin does nothing about Covid 19

 

[eagle1462010]

ivermectin does nothing about Covid 19

Good Boy. Your masters are proud of you.

 

[John Edgar Slow Horses]

Good Boy. Your masters are proud of you.

Ivermectin works on MAGA parasites.

 

[LeroyDumonde]

ivermectin does nothing about Covid 19

According to science, you're wrong.

 

[John Edgar Slow Horses]

The science says, Leroy, Ivermectin does nothing about curing Covid. It is an anti-parasitic medicine not anti-viral.

 

[LeroyDumonde]

The science says, Leroy, Ivermectin does nothing about curing Covid. It is an anti-parasitic medicine not anti-viral.

Ivermectin has anti-parasite, anti-viral, and anti-fungal properties. This has been known for decades. I know you're Slow but do try to keep up.

 

[John Edgar Slow Horses]

It has no documented anti-viral treatment for Covid.

 

[LeroyDumonde]

Yes there is.

 

[John Edgar Slow Horses]

Nope.

 

[Leo123]

Don’t you know ivermectin is horse paste? CNN told me. They never lie.

Horses take many meds that humans take. NSAIDS for pain, antibiotics, Benadryl, celecoxib, etc. but the dose is MUCH higher.