Just as potent as Sorensen, et al, is the magnificent work of Mona Rahalkar et al, first posted to USMB on 4 Jun 2021, recalling that this report links to the Mojiang miners going into the hospital (as [italics]) Fau Chi is testifying to the U.S. Senate (26 Ap 2012), ironically enough, about dual-use:
Because SARS-CoV-2 D614G (aspartic acid-to-glycine) mutation links precisely to the VSV of ebola vaccine, a Pubmed search ‘ebola aspartic glycine,’ yielded no references. Next, an ‘ebola mutations’ search yielded Niemann-Pick references, so a refined search was attempted: ‘Niemann-Pick aspartic...
SARS-CoV-2 infection can result in the development of a constellation of persistent sequelae following acute disease called post-acute sequelae of COVID-19 (PASC) or Long COVID[1][1]–[3][2]. Individuals diagnosed with Long COVID frequently report unremitting fatigue, post-exertional malaise, and...
www.medrxiv.org
'....Long COVID groups reported significant increase in intensity of symptoms and dramatically worsened quality of life....exhausted T cells suggest chronic antigens stimulating these T cells. What they are we do not know yet.'
In Feb 2018, Baric and Sheahan publish a GoF paper concerning the moratorium, and its clear they want to push remdesivir. They lament the lag in therapeutics. Thus, it should be kept in mind that two female scientists have already pioneered this trajectory for coronaviruses:
21 Feb 2018 Sheahan & Baric, Is Regulation Preventing the Development Of Therapeutics That May Prevent Future Coronavirus Pandemics?
You better fucking pay attention. Just look at his followers. What I pay attention to is actions. I have never gone on Twitter. I pay attention to Fauci's actions as the NIH officer who signed off on Gain Of Function research at the Wuhan Virology Lab and then lied to Congress about his...
In this thread, we have already linked GATA to ACE2. Sars-Cov-2's near-relative, RaTG13 from the Tongguan copper mine, has been refuted as academic fraud by Zhang. Here we link Claire's (post # 1,094) GATA-4 zinc-finger to Rhinolophus bat zinc-finger, recalling zinc used in the Zelenko protocol:
Daoyu Zhang, Anomalies in BatCov/RaTG13 Sequencing and Provenance
To this date, the most critical piece of evidence on the purposed “natural origin” theory of SARS-CoV-2, was the sequence known as RaTG13, allegedly collected from a single fecal sample from Rhinolophus Affinis. Understanding the provenance of RaTG13 is critical on the ongoing debate of the...
zenodo.org
'....Fig. 11 A viral sequence fused to a mRNA-like sequence: Rhinolophus ferrumequinum zinc-finger CCCH-type containing 12A (ZC3H12A), mRNA.'
'Introduction to FOG (Friend of GATA) and GATA-4.
The nuclear proteins Friend of GATA-1 (Fog-1) and Friend of GATA-2 (Fog-2) are transcriptional repressors that bind to members of the Gata family of transcription factors. The mammalian Fog-1 and Fog-2 genes can be identified by the presence of eight distinct CCHH or CCHC zinc fingers that bind to nucleic acid and protein, respectively.
Both Fog-1 and Fog-2 originated from a single Drosophila gene, U-shaped or Ush, and the conservation of CCHC zinc fingers in location and structure between these three proteins supports a conserved evolutionary function for the Fog and Ush genes. Fog-2 has been shown to be critical for normal cardiac and diaphragm development in humans and mice....
Mouse embryos that are homozygous null for Gata-4 die at E7.0-9.5 due to a failure of ventral morphogenesis and heart tube formation with cardiac bifida. However, Gata-4 mouse mutants created by gene targeting to prevent the interaction of the mutant Gata-4 protein with Fig-2 have had a similar cardiac phenotype To homozygous null Fog-2 mice.'
(Epstein, op cit, 118: Fog-2 (now ZFPM2) and GATA-4 and Congenital Heart Disease and Diaphragmatic Hernia)
We have placed the Zhang report alongside Epstein-Slavotinek's GATA chapter, above, linking it to Clair Bridges' CHD-GATA-4 and SARS-CoV-2 vaccine-induced amputation. Daoyu Zhang continues:
'Many of these anomalies points toward the fraudulent use of a mixed DNA library, rather than genuine mRNA, for the sequencing of SRX7724752, evident by the presence of widespread A-T ligation of unrelated dsDNA fragments that can only happen if the same library preparation process has been ran on dsDNA instead of ssRNA, which would constitute Academic fraud....indicating that the sequence did not derive from what the Wuhan Institute of Virology claimed to be....must be immediately invalidated and retracted.'
GATA-1 is the key transcription factor for the development of the erythroid, megakaryocytic, eosinophilic, and mast cell lineages. GATA-1 possesses the ability to self-associate, and this characteristic has been suggested to be important for GATA-1 function. To elucidate the roles...
pubmed.ncbi.nlm.nih.gov
'In summary, these results demonstrate that the ability of Gata-1 to self-associate Is required to sustain both primitive and definitive erythropoiesis....Gata-1.05/Y mice bearing the Gata-1-3KA mutant transgene die in utero. Intriguingly, Gata-1.05/Y mice expressing the 3KA mutant that escaped from embryonic lethality showed moderate anemia but no thrombocytopenia.'
Newborns with congenital heart disease (CHD) born at term gestation demonstrated altered erythropoiesis. Term newborns with CHD have decreased hemoglobin levels despite having red blood cell indices consistent with stress erythropoiesis, suggesting an incomplete compensatory response to in utero...
pubmed.ncbi.nlm.nih.gov
'....Newborns with congenital heart disease born at term gestation demonstrated altered erythropoiesis....suggesting incomplete compensatory response to in utero physiologic disturbances associated with CHD. The etiology is unknown.'
Transferrin and its receptor involved in impaired erythropoiesis, above, will link to ebola, its vaccine, and the D614G Sars-Cov_2 mutation linked to ebola vaccine. USMB search: D614G pseudovirus particles vsv.
Membrane-associated RING-CH-type 8 (MARCH8) strongly blocks human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (Env) incorporation into virions by downregulating its cell surface expression, but the mechanism is still unclear. We now report that MARCH8 also blocks the Ebola virus...
pubmed.ncbi.nlm.nih.gov
This report will link furin to the anomalies of RaTG13 as academic fraud on the part of Wuhan Institute of Virology (post #1,106):
Oct 2002 Alzheimer's / Furin Maturation of Proprotein Substrates
Production of affordable coronavirus disease 2019 (COVID-19) vaccines in low- and middle-income countries is needed. NDV-HXP-S is an inactivated egg-based Newcastle disease virus (NDV) vaccine expressing the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)...
pubmed.ncbi.nlm.nih.gov
'....by removing the polybasic furin cleavage site.'
We know that early-onset Alzheimer's can happen as early as 27 years of age (Japan). As the reader can see in the Zhang fraud report (post # 1,105), references including this one having to do with ageing:
'Ref. #24: Growing Old Yet Staying Young: The Role of Telomeres in Bats' Exceptional Longevity, Science Advances, 7 Feb 2018'
If the virus was deliberately introduced,in Wuhan, then elderly and obese would be the major target.
The Shining
'Clade X 2018. Then, on May 15, 2018, inside the darkened ballroom of Washington's Mandarin Oriental Hotel, foreboding military music introduced another "pandemic/biowarfare preparation exercise" hosted by the Johns Hopkins Center for Health Security (formerly the Hopkins Population Center, which Gates and NIH fund). The daylong event, dubbed Clade X, "simulate[d] the response to a fictitious bioengineered pathogen for which there is no vaccine." Hoping to reduce world population, an elite cult released their genetically engineered bug from a Zurich lab. The disease spreads first to Germany and Venezuela and then to the United States, killing 100 million people globally as "healthcare systems collapsed, panic spread, the US stock market crashed." '
(Kennedy, The Real Anthony Fauci, pp. 418-19)
Mutations in Alzheimer's presenilin protein prompt interest in bat longevity. Indeed, the ebola-linked SARS-CoV-2 mutation, "Fau Chi's Mutation," occurred in both China and Germany within one week of each other.
Furin catalyses a simple biochemical reaction--the proteolytic maturation of proprotein substrates in the secretory pathway. But the simplicity of this reaction belies furin's broad and important roles in homeostasis, as well as in diseases ranging from Alzheimer's disease and cancer to anthrax...
Quay @ 15 Aug: Oh shit! What do you do first? You blast the spike protein against Urbani strain of SARS-CoV-1 to look 4 differences...."human specific" furin cleavage site of lung ENAC....RRARSVS.'
But SARS-CoV-2 sequence is RRARSVA. So an alanine is removed, replaced by a serine. Because we already know from previous posts that the branched-chain amino acids are what the coronavirus genome uses for substitutions as part of its natural modus operandi, apparently on a whim, at random (branch-chain aminos: I,V,L).
India News: With 16,251 recoveries reported in the last 24 hours, the country's recovery rate has reached 98.58 per cent. The total number of patients who have re