COVID-19’s Biological Politics

[badger2]

Satoshi Omura's first ivermectin experiment involved a nematode from mice. Here is linked an onchcercid nematode to South Africa on the Omicron trajectory, first showing that the target nematode genus occurs both in South Africa and China:

Culicoides as Vector of Acanthocheilonema in South Africa / Bluetongue Virus

Culicoides spp. (Diptera: Ceratopogonidae) as vectors of bluetongue virus in South Africa - a review - PubMed

The aim of this paper is to consolidate vector competence studies on Culicoides midges (Diptera: Ceratopogonidae) as vectors of bluetongue virus (BTV) done over a period 25 years at the ARC‑Onderstepoort Veterinary Institute in South Africa. In 1944, it was demonstrated for the first time in...

pubmed.ncbi.nlm.nih.gov

Ivermectin used for river blindness (onchocercosis) links to West Africa and ebola country:

1951: Acanthocheilonma (Onchocercidae) / Niger Delta

Studies on the epidemiology of filariasis in West Africa, with special reference to the British Cameroons and the Niger Delta. II. The influence of town and village evolution and development on the incidence of infections with Loa loa and Acanthochei

Studies on the epidemiology of filariasis in West Africa, with special reference to the British Cameroons and the Niger Delta. II. The influence of town and village evolution and development on the incidence of infections with Loa loa and Acanthocheilonema perstans

pubmed.ncbi.nlm.nih.gov

Intermediate host of Acanthocheilonema in India and China is Hippobosca:

Jul 2011: India-China / Hippobosca / Feral Dogs / Acanthocheilonema

Hippobosca longipennis--a potential intermediate host of a species of Acanthocheilonema in dogs in northern India - PubMed

This study provides evidence for a potential intermediate host-parasite relationship between H. longipennis and the canine Acanthocheilonema sp.? nov. in northern India.

pubmed.ncbi.nlm.nih.gov

Next will be shown that a protease inhibitor from Acanthocheilonema is anti-asthmatic.

 

[badger2]

The football player may or may not have had asthma during childhood or as an adult. Before linking the cystatin from the nematode to coronaviruses, it is shown that it is anti-asthmatic:

Acanthocheilonema Cystatin / Asthma

A helminth immunomodulator reduces allergic and inflammatory responses by induction of IL-10-producing macrophages - PubMed

The coincidence between infections with parasitic worms and the reduced prevalence of allergic disease in humans and in animal models has prompted the search for helminth molecules with antiallergic and antiinflammatory potential. We report herein that filarial cystatin, a secreted protease...

pubmed.ncbi.nlm.nih.gov

'....Filarial cystatin, a secreted protease inhibitor, suppresses TH-2-related inflammation and ensuing asthmatic disease in a murine model of OVA-induced allergic airway responsiveness.'

Cystatin Superfamily / AHSG

Friends and relations of the cystatin superfamily--new members and their evolution - PubMed

The cystatin "superfamily" encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. In recent years, several new members of the superfamily have...

pubmed.ncbi.nlm.nih.gov

Aug 2011: SARS-CoV Susceptibility / AHSG

Genetic variation of the human α-2-Heremans-Schmid glycoprotein (AHSG) gene associated with the risk of SARS-CoV infection - PubMed

Genetic background may play an important role in the process of SARS-CoV infection and SARS development. We found several proteins that could interact with the nucleocapsid protein of the SARS coronavirus (SARS-CoV). α-2-Heremans-Schmid Glycoprotein (AHSG), which is required for macrophage...

pubmed.ncbi.nlm.nih.gov

 

[badger2]

Pfizer's mRNA vaccine failure in saliva compare with the evolution of lipocalins and serpins in tick saliva. The serpins will link the biological politics of SARS-CoV-2 in the deer-tick-mouse cycle of diseases such as Lyme. Interesting facts come from the soft tick, Ornithdoros moubata (African Sand Tampon), that inhabits human rest stations in Africa, and can go for five years without a blood-meal.

On 23 Jun 2021, post #520 of this thread mentioned vulpeculin, a lipocalin of the Australian brush-tail opposum, Trichosurus vulpecula, while post #516 linked Wobbly Possum Disease Nidovirus (contains Coronaviridae) in the same animal and a Type D retroviral element, which is an HIV-AIDS link by which to compare any Omicron resonance that may arise in the investigation of South African mice and humans:

23 Jul 2021 Posts #516 & 520

COVID-19’s Biological Politics

The mite, Notoedres cati, also occurs on another natural reservoir of SARS-CoV: Racoon Dog (Nyctereutes procyonoides viverrinus) / Notoedres cati https://pubmed.ncbi.nlm.nih.gov/25397999 ’....The cat mite (Notoedres cati) was the cause in one raccoon dog (Nyctereutes procyonoides viverrinus)...

www.usmessageboard.com

Immunomodulatory Proteins in Tick Saliva From a Structural Perspective - PubMed

To feed successfully, ticks must bypass or suppress the host's defense mechanisms, particularly the immune system. To accomplish this, ticks secrete specialized immunomodulatory proteins into their saliva, just like many other blood-sucking parasites. However, the strategy of ticks is rather...

pubmed.ncbi.nlm.nih.gov

'....In 2020, a monument to ticks was erected in the Russian city of Ufa. The tick, casted in silver, sits upon a half-metre-high stone from the Ural Mountains with the inscription, "Same as you, I want to live," which according to the artists should underline that ticks are a part of nature despite negative connotations.
....
Lipocalins
OMCI stands for Ornithodoros moubata Complement Inhibitory Protein, a 17 kDa lipocalin. Being a C5 inhibitor, OMCIU has drawn attention as a possible alternative to the already marketed C5 inhibitor, eculizumab, which is considered the most expensive drug in the world with an annual treatment price reaching $500K per patient.
In two case studies, recombinant OMCI (also known as coversin or rEV576, Akari Therapeutics) has been used successfully to treat thrombotic microangiopathy (TMA) associated with hematopoietic stem cell transplantation and paroxysmal nocturnal haemoglobinuria (PNH).
....
Conjugation of coversin to a long Pro-Ala-Ser polypeptide (PASylation) dramatically increases circulation time without interfering with anti-complement activity.

Serpins
Being recognized as a protein family in 1980, over 1500 members are known to date....Despite low sequence homology, all serpins adopt a similar three-dimensional fold embodying the N-terminal helical and C-terminal beta-barrel domains. The latter consists of three beta-sheets A-C and the long, flexible reactive center loop (RCL) containing the scissile bond between residues P1 and P1'.

Upon cleavage of this bond, the RCL undergoes a conformational change and incorporates itself into beta-sheet A, forming a hyperstable relaxed conformation. As a result, a serine protease, remaining covalently attached to a P1 residue in the form of an acyl-enzyme complex, is moved away from the top of a serpin. That causes distortion of a protease's catalytic triad and its inability to hydrolyze an ester bond between serine and P1 residues, making binding irreversible (suicidal).

Serpins whose RCL cannot form a hyperstable insert to the beta-sheet lack classical inhibitory activity, but can act as transporters and regulators of blood pressure and vasomotor activity. Due to the suicidal nature of serpin binding, serpins play a crucial role in enzymatic cascades where tight regulation is necessary, such as in blood coagulation and activation of the complement system.

Blood-sucking arthropods, including ticks, acquired diverse serpins in their saliva to counteract the host hemostasis and immune responses, with most of the tick serpins described as having anti-hemostatic functions.'

 

[badger2]

COVID-19's Biological Politics, continued

The following report is a stunning and scientifically strong document for the unnatural origins for the SARS-CoV-2 virus, and elegantly monkey-wrenches attempts to stigmatize the argument as conspiracy theory:

https://www.minervanett.no/files/2020/07/13/TheEvidenceNoNaturalEvol.pdf

'....Since, regrettably, international access has not been allowed to the relevant laboratories or materials, since Chinese scientists who wished to share their knowledge have not been able to do so and indeed since it appears that preserved virus material and related information have been destroyed, we are compelled to apply deduction to the published scientific literature, informed by our own biochemical analyses.

We refute pre-emptively objection that this methodology does not result in absolute proof by observing that to make such a statement is to misunderstand scientific logic. The longer the chain of causation of individual findings that is shown, especially converging from different disciplines, the greater the confidence in the whole. We posit that the evidence below attains a high level of confidence.'

 

[badger2]

The politics and propaganda happened swiftly in the media, with Andersen et al's paper being a prominent addition to daily news. Sorensen, Dalgleish and Susrud (above) continue:
'Wan et al are cited by Andersen et al but offer them no support. Wan et al say, correctly in our opinion, that computational structural modeling of complex Virus-receptor interactions can be used for structural predictions and that such models can be potentially used for Gain-of-Function modelling.

It is well known that models have been developed from data generated in animal model systems such as palm civet. Wan et al sat that the SARS-CoV-2 binding to the ACE2 receptor confirms the accuracy of the structural predictions. Therefore the data and conclusion in Wan et al contradicts Andersen et al's opinion that it is improbable that the virus could have emerged through laboratory manipulations.

There is a similar problem in (Sheahan et al, 2008). This deals with research on a civet strain SZ16 and the infective strain of SARS-CoV, Urbani. These strains were used to create a chimeric virus IcAZ16-S. Sheahan et al. Go on to explain that by in vitro evolution of the chimeric virus icSZ16-S on human airway epithelial (HAE) cells in the lab, they have been able to produce two new viruses binding to HAE cells. Therefore, this reference supports the very opposite of Andersen et al's hypothesis. We are immediately wary of any paper containing such egregious errors.'

 

[badger2]

In their report, Sorensen, Dalgleish and Susrud expound on the porcine coronavirus, SADS-CoV of 2017. Reviewing the spike with that of Omicron mutations yield three sites of interest:

Omicron T95I / SADS-CoV I95
Omicron G142D / SADS-CoV D142
Omicron S375F / SADS-CoV S375

 

[badger2]

Parts of monkeys, non-human primates, dried bushmeat. These stupid Africans should be put on a leash:

13 Jan 2021 St. Paul International Airport Intercepts Deadly Bushmeat

Minnesota CBP Stops the Deadly Introduction of Bushmeat in the U.S.

Securing America's Borders

www.cbp.gov

'....Liberia....'

 

[badger2]

Chinese are calling it "coronary pneumonia" on the threshold of the Olympic Games, so we'll be tracking coronary symptoms and evidence back to bloodsuckers of the masked palm civet, Paguma larvata, and raccoon dog, Nyctereutes, reservoirs of SARS-CoV-1:

åç«æçå½±å 大ä¼å丰ç°å¨æ´¥é¨åå·¥åææ¶å³é

受疫情的影响 大众和丰田在津部分工厂暂时关闭,丰田,大众汽车集团,一汽-大众,大众汽车,一汽丰田,工厂

auto.163.com

'....Affected by the epidemic in Tianjin, some factories of Volkswagen and Toyota are temporarily closed "affected by the current round of coronary pneumonia in Tianjin." '

 

[badger2]

Surfaces in the news

We have already posted on the porcine coronavirus TGEV that can subsist on inanimate surfaces such as steel for up to 28 days, and as far as is known, similar information is lacking for Delta or Omicron on surfaces.

Arrive in Mail from Canada?

Canadian letter claimed to be potential source of Beijing Omicron infection

City’s first case of the Covid-19 variant received a letter from Toronto which had traces of the virus, health authorities say.

www.scmp.com

 

[badger2]

Surfaces in the news

We have already posted on the porcine coronavirus TGEV that can subsist on inanimate surfaces such as steel for up to 28 days, and as far as is known, similar information is lacking for Delta or Omicron on surfaces.

Arrive in Mail from Canada?

Canadian letter claimed to be potential source of Beijing Omicron infection

City’s first case of the Covid-19 variant received a letter from Toronto which had traces of the virus, health authorities say.

www.scmp.com

'....Pang Xonghuo, deputy director of Beijing CDC said the city's first COVID-19 patient to be diagnosed with Omicron variant had received a letter mailed from Canada on 7 Jan. "We don't rule out the possibility that the person was infected through contacting an object from overseas," she said. Chinese authorities have repeatedly said they are finding the coronavirus on contaminated imports usually frozen goods.

Some researchers and health authorities overseas have raised doubts about this method of transmission, arguing' the virus does not survive long enough on surfaces.'

A porcine And a murine coronavirus can subsist for up to 28 days:

Post #391 Germany, 6 Feb 2020

Snake Meat......source of chinese virus

We have sent a communication to Italy in regard to the subspecies and type locality of Bungarus multicinctus wanghaotingi. It may not have been investigated. 11 Feb 2020 Coronavirus Likely Jumped from Bats to an 'Intermediate Host' Before Infecting Humans, WHO Says Coronavirus likely jumped...

www.usmessageboard.com

 

[badger2]

Gamaleya's Sputnik V has been accepted for international travel, and Israelis who were previously prevented from traveling to
"red zones" to everyone's surprise were now open borders:

17 Jan 2021 Sputnik V Accepted for International Travel to Australia

Russia's covid vaccine Sputnik V accepted for international travel to Australia

The regulator explained that additional data on the Russian vaccine's effectiveness showed that two doses of Sputnik V demonstrated an average efficacy against symptomatic COVID-19 infection of 89 per cent and against hospitalization or death of 98-100 per cent

www.livemint.com

'....Gamaleya Institute....'

15 Jan 2022 Novaya Gazeta
Vycherkuli iz "krasnoi zony"
Removed from the "Red Zone"
'....Kotia rossiiskaya pokane vkhodit v chislo priznannykh VOZ problemu udalos' reshit na politicheskom urovne.
....Although the Russian vaccine is not yet among those recognized by the WHO, the problem has been resolved at the political level.

Priletaiushchie rossii turisty, pomimo obiazatel'nogo dlia vsekh pribyvshikh PtsR-tests sdaiut eshche i serologicheski i testa na antitela.
Tourists arriving from Russia, in addition to the mandatory PCR test for all arrivals, also pass a serological test for antibodies.

Tol'ko posle polucheniia poluzhitel'nogo rezultata na serologiiu (kak pravilo, v techenie sutok-dvukh) oni imeiut pravo prervat karantin.
Only after receiving a positive result for serology (usually within a day or two), they have the right to interrupt quarantine.

V izrail'skom pravitel'stve opasaiutsia naplyva rossiiskikh turistov, potomu chto neiasno, naskol'ko effektiven "Sputnik V" protiv "Omicrona".
The Israeli government fears an influx of Russian tourists because it is not clear how effective Sputnik V is against Omicron.

Poetomu tot fakt, chto Izrail' otkryt, ne afishiruetsia.
Therefore, the fact that Israel is open is not advertised.'

 

[badger2]

The French are trying to differentiate between Delta and Omicron by looking for the L452R mutation. As far as is known, Homo spaiens has yet to bring up the significance of the vaccine-linked N969K Omicron mutation in the media:

Post #22 Flutrackers: France

France - Media: MoH reports 8 possible COVID-19 Omicron variant cases - November 28, 2021, 1 confirmed case in Reunion - FluTrackers News and Information

France - Media: MoH reports 8 possible COVID-19 Omicron variant cases - November 28, 2021, 1 confirmed case in Reunion

flutrackers.com

'....In order to try to identify more effectively the propagation of Omicron variant in France, these specialists are based in particular on the proportion of tests exhibiting the "L452R" mutation, present in the Delta variant, but absent in Omicron.'

 

[badger2]

More evidence apart from Kennedy's book surfaces, suggesting that Eco Health Alliance is a CIA front organization, and mentions Baric's chimeravirus:

18 Jan 2022 Was Peter Daszak Working for the Central Intelligence Agency?

Was Peter Daszak Working For The Central Intelligence Agency?

An EcoHealth Alliance whistleblower steps forward.

kanekoa.substack.com

'....There was no way that the data collected or the models being developed, could predict transmission or pandemics....partnered with Dr. Ralph Baric of the University of North Carolina and Dr. Shi Zhengli of Wuhan Institute of Virology....Baric successfully created a "chimeric" coronavirus in 2015....what went on to be a potential precursor of SARS-CoV-2.'

 

[badger2]

But Daszak co-authored the discovery paper on this virus, RsSHC014, that went on to be SHC014-MA (mouse-adapted) originally collected on 18 Ap 2011 at Kunming, Yunnan, China.

 

[badger2]

Kunming is also the link to Bejing CDC's Yong-zhen Zhang, who, co-authoring with Australia's E.C. Holmes, described fatal tick-borne viruses, vectored in China by the same Asian Longhorned Tick in Missouri and Tennessee for the fatal Heartland tick-borne virus. Y-Z Zhang attended the Kunming Institute of Zoology, which is the E.C. Holmes link.

 

[badger2]

Kennedy posits the CIA passages toward the end of the book, aptly quoting Sharav:

'....and one of the lockdown's most influential propagandists, Anderson Cooper, who has acknowledged that he responded to a CIA recruitment poster while attending Yale and worked an indeterminate number of summers thereafter at Langley.
....
"This should be a medical and not be a military operation," Holocaust survivor and medical ethics advocate Vera Shirav told me. "It's a public health problem. Why are the military and the CIA so heavily involved? Why is everything secret? Why can't we know the ingredients of these products, which the taxpayers financed?

Why are all their emails redacted? Why can't we see the contracts with vaccine manufacturers? Why are we mandating a treatment with an experimental technology with minimal testing? Since COVID-19 harms fewer than 1 percent, what is the justification for putting 100 percent of the population at risk? We need to recognize that this is a vast human experiment of all mankind, with an unproven technology, conducted by spies and generals primarily trained to kill and not to save lives." What could possibly go wrong?'
(Kennedy, The Real Anthony Fauci, pp. 432 & 435)

 

[badger2]

A report from France-Belgium shows long COVID shortness of breath a year after infection:

France-Belgium Long COVID Dyspnea / Myocardial Dysfunction

Subclinical Myocardial Dysfunction in Patients with Persistent Dyspnea One Year after COVID-19

Long coronavirus disease 2019 (COVID-19) was described in patients recovering from COVID-19, with dyspnea being a frequent symptom. Data regarding the potential mechanisms of long COVID remain scarce. We investigated the presence of subclinical cardiac dysfunction, assessed by transthoracic...

www.mdpi.com

'....one year after COVID-19 in more than a third of recovered patients....decrease in myocardial performance subclinical cardiac dysfunction.'

 

[badger2]

It is known that a grooming civet, Paguma larvata, reservoir of SARS-CoV, can swallow its ticks, thereby eating its own blood and ingesting SARS-CoV, now directed to its gastrointestinal tract. One link to Fau Chi's dog experiments is Lyme disease in canines vectored by the black-legged tick, Ixodes scapularis, even though this tick does not attack Asian civets, as far as is known. This report is from Athens, Georgia:

(2016) Canine Lyme Synovial Lesions

Demonstration of the ability of a canine Lyme vaccine to reduce the incidence of histological synovial lesions following experimentally-induced canine Lyme borreliosis - PubMed

Lyme disease in dogs can be effectively prevented by vaccination against antigens expressed by the spirochete Borrelia burgdorferi during transmission by the tick vector Ixodes sp. Lyme vaccine efficacy has traditionally been based on indicators of infection following wild-caught tick challenge...

pubmed.ncbi.nlm.nih.gov

 

[badger2]

Note that the dogs used in the post #958 study were beagles.

 

[badger2]

Fau Chi's beagle experiments will link to Lyme disease vaccine. It was posted this morning in the Flutrackers Science Library forum @ 5:49 AM, the very minute badger looked at the clock upon awakening:

Dec 2021 Athens, Greece: De Novo Minimal Change Disease Following Vaccination with Pfizer BioNTech SARS-CoV-2 Vaccine in a Living Kidney Donor

De Novo Minimal Change Disease following Vaccination with the Pfizer/BioNTech SARS-CoV-2 Vaccine in a Living Kidney Donor - PubMed

Coronavirus disease 2019 has developed as a pandemic. Immunization with the introduction of vaccines against COVID-19 seems be the only way to end this pandemic. We report on a case of a kidney donor, who developed minimal change disease (MCD) within 4 days post-vaccination with the SARS-CoV-2...

pubmed.ncbi.nlm.nih.gov

'....Two days later, she presented with a relapse of full-blown nephrotic syndrome with preserved renal function.'

Dropping back in time to link other studies:

Sept 2021 Komaba H, et al

Relapse of Minimal Change Disease Following the Pfizer-BioNTech COVID-19 Vaccine - PubMed

Relapse of Minimal Change Disease Following the Pfizer-BioNTech COVID-19 Vaccine

pubmed.ncbi.nlm.nih.gov

Aug 2021 Mancianti N, et al

Minimal change disease following vaccination for SARS-CoV-2 - PubMed

Minimal change disease following vaccination for SARS-CoV-2

pubmed.ncbi.nlm.nih.gov

Aug 2021 Switzerland

Letter regarding "Minimal change disease relapse following SARS-CoV-2 mRNA vaccine" - PubMed

Letter regarding "Minimal change disease relapse following SARS-CoV-2 mRNA vaccine"

pubmed.ncbi.nlm.nih.gov

'....Vaccination (notably hepatitis B, influenza, measles and rubella) is a recognized trigger for the relapse of idiopathic nephrotic syndrome, and SARS-CoV-2 mRNA vaccine is probably to be added to the list of at-risk vaccines.'

We kept following the trajectory at Pubmed, noticing an HIV link:

Nov 2018 HIV / Minimal Change Disease

Minimal change nephrotic syndrome in patients infected with human immunodeficiency virus: a retrospective study of 8 cases - PubMed

In patients with MCNS occurring in a context of HIV infection, podocyte injury seems to be associated with CMIP induction rather than renal HIV infection but further studies are needed to determine the molecular link between these two conditions.

pubmed.ncbi.nlm.nih.gov

Recalling that retroviral elements can integrate into the coronavirus genome, and that we had already made the tick connection to SARS-CoV-1, we added Borrelia to the minimal change search, finding one entry:

Feb 2012 Poland: Minimal Change Disease Secondary to Borrelia burgdorferi Infection

Minimal-Change Disease Secondary to Borrelia burgdorferi Infection - PubMed

Lyme borreliosis is a chronic illness caused by tick-transmitted spirochete Borrelia burgdorferi. Borreliosis can be extremely threatening if it is not diagnosed and treated in early stages. Kidneys are not typically involved in the disease. However, in infected dogs, Lyme nephritis is present...

pubmed.ncbi.nlm.nih.gov

While on that webpage, noticed was this report in the sidebar column:

2016 Athens, Georgia: University of Georgia and Merial, Inc. / Canine Lyme Synovial Lesions / Beagles

Demonstration of the ability of a canine Lyme vaccine to reduce the incidence of histological synovial lesions following experimentally-induced canine Lyme borreliosis - PubMed

Lyme disease in dogs can be effectively prevented by vaccination against antigens expressed by the spirochete Borrelia burgdorferi during transmission by the tick vector Ixodes sp. Lyme vaccine efficacy has traditionally been based on indicators of infection following wild-caught tick challenge...

pubmed.ncbi.nlm.nih.gov

The same University of Georgia author, above, links again to France:

Bristol Veterinary School, University of Bristol, UK; Boehringer-Ingelheim, Athens, Georgia; Boehringer-Ingelheim, Lyon, France / Characterization of Recombinant OspA in Two Different Borrelia Vaccines with Respect to Immunological Response and Its Relationship to Functional Parameters

Characterization of recombinant OspA in two different Borrelia vaccines with respect to immunological response and its relationship to functional parameters - PubMed

We hypothesize that these structural differences may account for the superior immunogenicity of the nonadjuvanted monovalent recombinant OspA vaccine in dogs over the adjuvanted OspA fraction of the OspA/OspC vaccine.

pubmed.ncbi.nlm.nih.gov

This trajectory for example, will prompt further scrutiny of relapsing fever ticks, their spirochetes, viruses and rickettsial endosymbionts.