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Ritonavir inhibits CYP2D6. These drug interactions are not well documented:
Jun 2021 CYP2D6 Coronavirus
’....Ritonavir inhibits CYP2D6....Many cardiology, pulmonology, and intensivist physicians have never been exposed to clinical scenarios requiring co-prescription of cardiac and antiviral therapies.’
Oct 2020 Spain: CYP2D6 / SARS-CoV / Loss-of-Function
Jun 2021 CYP2D6 Coronavirus
Lopinavir-Ritonavir in SARS-CoV-2 Infection and Drug-Drug Interactions with Cardioactive Medications - PubMed
Lopinavir-ritonavir combination is being used for the treatment of SARS-CoV-2 infection. A low dose of ritonavir is added to other protease inhibitors to take advantage of potent inhibition of cytochrome (CYP) P450 3A4, thereby significantly increasing the plasma concentration of coadministered...
pubmed.ncbi.nlm.nih.gov
Oct 2020 Spain: CYP2D6 / SARS-CoV / Loss-of-Function
Towards Accurate Genotype-Phenotype Correlations in the CYP2D6 Gene - PubMed
Establishing accurate and large-scale genotype-phenotype correlations and predictions of individual response to pharmacological treatments are two of the <i>holy grails</i> of Personalized Medicine. These tasks are challenging and require an integrated knowledge of the complex processes that...
pubmed.ncbi.nlm.nih.gov