It is my understanding that the cocktail of zinc, azithromycin and HCQ is effective when used early on, not once they have progressed to a point they need to be hospitalized. Those patients will not respond to HCQ. Out patient physicians were not given access to HCQ as early as March. In fact, pharmacyās begin NOT filling prescriptions shortly after Trump mentioned the drug. Hospital pharmacies were filling those prescriptions but obviously for patients who had already progressed to the point of hospitalization, where we know that HCQ is ineffective. We should have been and currently should be prescribing HCQ in an out-patient setting along with zinc and azithromycin when patients are positive and symptomatic. This is being done around the world and has been effective. Most of the studies I have read have been focused on giving the drugs when they have progressed well passed the time for them to be effective.
Again, this is all from my understanding and it is obviously second hand information.
Article below states my point.
Study shows hydroxychloroquine may be effective for outpatients with COVID-19
You should notice how the efficacy of HCQ is a constantly moving target. At first it was a good treatment for COVID, so we tried it in hospitals and it didn't work. Then it was that the dose too low. Then it was that the dose is too low. Then you had to add azithromycin. Then you had to add zinc. Then you needed to use it in outpatients. Then you needed to use it in people without severe symptoms. Every time a study shows it fails, then the parameters for which it works changes slightly so that people can continue to claim it's effective. This in itself should give you some skepticism about it's efficacy and skepticism of the quality of people pushing it.
Know why outpatient physicians weren't given access? Because we thought it was effective for inpatients and we wanted to use the supply for the people who were sick. Not to mention a bunch of unscrupulous physicians were prescribing large supplies for themselves and their friends because they thought it was going to be a cure as well. Now it's just not used to supply issues aren't a big problem anymore but there was a supply problem for a while, early on.
I just actually read this study from the world famous Zelenko, the guy no one ever heard of because he's not an academic, he's just some community doctor who got internet famous for saying the right things. As I've stated before, the media is a garbage place to get scientific information because the vast majority of journalists (or bloggers or whoever) are barely scientifically literate enough to do justice to these complex issues. This article is actually better than most but still focuses far too much on the media controversy.
The study itself is absolute garbage. The comparison group is some amorphous "public reference data" and does basically no explanation of where the data came from. Furthermore, the reference group has zero characteristics outside the fact that they were diagnosed with COVID and were hospitalized. We don't know their age, comorbid conditions, or even where they presented. It's an absolute joke to even try to use this as a comparison tool. This article is going to be ignored for good reason, it's such low quality that it's absolutely useless to draw any conclusions from. Not to mention it's published in a really obscure journal.