You're not wrong if you're arguing that all of those are examples of federal over-reach that lack Constitutional support. Two more examples are the federal Department of Education, and the Department of Housing and Urban Development. People have just gotten so used to these federal agencies being ever present that it's hard to imagine a time before they existed. But there is no Constitutional authority for either to exist, and both of those bloated bureaucracies that cost the taxpayers billions of dollars each year should be axed, hopefully by a future president that runs as a fiscal and constitutional conservative AND actually governs that way.
As for your OSHA vaccine mandate example, the Supreme Court actually struck that down, so at least that example of federal overreach was reigned in.
As for the trucking example, the purported Constitutional authority for the federal government to issue and enforce the FMCSRs and HMRs is the Commerce Clause. But that's probably the most misapplied section of the entire Constitution, as the federal government almost always tries to justify unconstitutional federal overreach by invoking the Commerce Clause. Those attempts have been shot down many times, but it's also gone unchallenged many times, and also upheld a few times involving rather tenuous applicability.
As for the topic at hand, I don't envision Congress passing any federal abortion legislation in the foreseeable future, given that the forthcoming SCOTUS decision (if consistent with the leaked draft) clearly spells out the absence of Constitutional support for a federal position on abortion. Any such legislation would be ripe for immediate challenge to the Supreme Court.