Ebola vaccine is based on a sandfly-vectored virus, VSV (a rhabdovirus). The precise SARS2 mutation that links to increased production of VSV pseudoparticles, is the D614G mutation. This is the mutation that Fau Chi gets backwards in his video, already posted to USMB. Next, we link the RGD motif to this New World sandfly:
Putative RGD-Containing Peptide from Lutzomiya longipalpis
httsp://uniprot.org/uniprotkb/Q9XZ49/entry
'....PNPRGDYRRR....'
Recalling Mary C. Guttieri's / Robert F. Garry's patent collaborations which include lyssaviruses, Dilyana's report for Georgia coronaviruses (post# 1,487) states:
'For example, West Caucasian bat virus (WCBV) was isolated from an insectivorous bat (Miniopterus schreibersii) in the Russian part of the Great Caucasus Ridge -- 300km from the Georgian border. This virus, and related viruses Ikoma and Llieda viruses is currently the most divergent member of lyssavirus genus.
Commercially available rabies biologics do not provide protection against WCBV. The virus is pathogenic for laboratory animals (such as mice and hamsters) but its significance for public health is unknown given that rabies diagnosis in Georgia, similar to other countries of Eastern Europe, is typically clinical in the majority of cases, and is not supplemented by virus identification.
The objectives of the project will be: characterization of DFA positive lyssaviruses by molecular methodologies; study prevalence of coronaviruses in Georgian bats; comparison of human and bat lyssaviruses. In addition, although the significance of bat as reservoirs of zoonotic diseases in the Caucasus region is unknown, we do know that WEST Caucasian bat virus circulates in Miniopterus schreibersii bats in the area.
The same bat species was recently implicated as reservoir of a novel filovirus in Spain....Finding new isolates of WCBV or novel lyssaviruses and coronaviruses in bats will provide new insights on the diversity of rabies and acute respiratory syndrome causative agents in the region.
This information can be of further use for vaccine development....No recent lyssaviruses or coronaviruses have been investigated....The incidence of rabies post-exposure prophylaxis (PEP) in Georgia is the highest in Europe....1 Feb 2014.'