Regional worldviews shape political parties and politics in the US. I think it is impossible for the US to escape regionalism, it can look past it in general consensus, or progress on some political issue, but it cannot escape it. Either Southerners, Northerners, Westerners, etc., are shaping US grand strategy, domestic and foreign, at any given time. So the question is, which region do you think will dominate the next 40 years? The last 30 years have been an interlude since what is called the "American Consensus" (which was rule over America by the North East), and this last 30 years has been aptly named "The End of the American Consensus". So what new Consensus will form? I think it will be a southern one, a more conservative, more Christian worldview. I think the Yankee nation is in decline. I think the Californians are largely on the run, they couldn't even get gay marriage passed. California is a likely contender to regional power in the United States, California is to the North East what Carthage is to Phoenicia. But, California is scheduled to lose 2 electoral seats through congressional reapportionment and conservative Southern states and mountain states are likely to pick up the change. The Yankee states are losing 1 each, 5 of them, including New York and New England states. Most of those states will likely lose a liberal seat in the reapportionment. I think the southern cultural engine of southern brand Christianity is also the only effective force of "colonization" left in the Union, the liberal indoctrination camps (Universities) don't seem to be very widespread at spreading culture, nor is liberal migration, since most liberal migration is to the south where generation after generation the south absorbs and assimilates new comers. The new consensus will form around the South, I do believe. And most likely centered on Texas.