ClaireH
Diamond Member
“The persistence of memory T cell responses to SARS-CoV for 17 years has been demonstrated9. Moreover, there is increasing evidence that SARS-CoV-2 VOCs rarely escape memory T cell responses elicited by SARS-CoV-2 infection or vaccination. “No sure what you call lasting immunity. The Prenominal vaccine which older folks should repeat every 10 years starts weakening after about 3 years but it is still very effective. On the other hand the yearly flu vaccine losses most of it's effectiveness after 4 or 5 months. The anthrax vaccine for humans require 5 does over 18 months and needs a booster yearly. The Yellow Fever vaccine has very short immunity and requires a booster at least every year.
Possibly including a live or attenuated virus does add to the length of immunity. However, vaccines that contain viruses have a nasty habit of creating a major infection, making some people very ill and occasion killing someone. That in itself is enough to drive people away from taking it. Clinical trials and ongoing studies show the mRNA vaccines are certainly effective past 3 months. Except for older folks, those with a compromised immune system, and those that took the Johnson and Johnson viral vector vaccine, a booster is not needed.
T cell-oriented strategies for controlling the COVID-19 pandemic - Nature Reviews Immunology
This Comment article proposes that T cell-oriented vaccine strategies should be considered to control the COVID-19 pandemic in the longer term, given declining levels of neutralizing antibodies with time after vaccination or infection and the emergence of viral escape variants.
www.nature.com
Let’s revisit this in a few years and see how things look. The information is known but privately held in check by certain orgs. They are going to have to release all of it to the public due to ethical researchers who are getting out their information.