one final caution concerns the issue of accountability. For Protestant churches, the Bible alone is the guide in matters of faith and practice. However, few people have the time to gain the skills and knowledge to accurately handle the word of God (2 Timothy 3:14-16). In classical education theology was taught last - for it builds on many other disciplines that cannot be learned from the Bible alone. Therefore, some degree of higher education was usually sought before one became a teacher of the word (James 3:1). The popular view today, however, is that the Holy Spirit teaches believers directly through the Bible. This idea might lead people to believe that whatever the group teaches is from God and is therefore safe from error. But the Bible does not teach that this is the case, and it is clear that most believers disagree on at least some issues, and most simply end up "interpreting" the Bible according to their churches' teaching anyway.
The answer to the interpretation issue requires another article, but the problem it creates becomes more ominous when dealing with home churches. The New Testament is full of warnings against heresies coming from within the church. Since it was written in the first century, these would actually be warnings regarding house churches. While this problem is certainly not limited to house churches, there is clearly no guarantee of protection from false teaching simply because the church changes its meeting format. Further, because home churches function as independent small groups, they need have no accountability to anyone but themselves. This makes it much more difficult to judge their teachings (in fact, the Jehovah's Witnesses cult began in exactly this manner). In contrast, larger congregations benefit from a plurality of elders, spiritually mature men (Titus 1:5-9) who are overseers of the flock, protecting them from false doctrine.
In conclusion, there is nothing unbiblical about Christians gathering together regularly in houses, or large buildings, or any other appropriate venue. The Bible does not, in fact, give any guidelines as to the proper gathering size or location. What it does do is explain what is to take place at those meetings (Hebrews 10; Colossians 3). So long as biblical teachings (orthodoxy) and practices (orthopraxy) are undertaken by those in assembly, it really does not matter what meeting format one chooses.