Fauci's folly, how long are we going to stand for this?

[badger2]

To seed a naturally-evolved virus would be the wisest choice. As we will show, deliberately introducing PRRSV into a herd has been done.

 

[badger2]

APOBEC-ADAR links to Alzheimer’s and prions:

APOBEC / Alzheimer’s

Possible editing of Alu transcripts in blood cells of sporadic Creutzfeldt-Jakob disease (sCJD) - PubMed

Editing of RNA molecules gained major interest when coding mRNA was analyzed. A small, noncoding, Alu DNA element transcript that may act as regulatory RNA in cells was examined in this study. Alu DNA element transcription was determined in buffy coat from healthy humans and human sporadic...

pubmed.ncbi.nlm.nih.gov

’....Enhanced ADAR correlated with A-G exchanges in dementia, AD, and SCJD was noted when compared to healthy controls as well as APOBEC-related C-T exchanges.’

 

[schmidlap]

In 2014 experts in the US convinced the Obama administration to put a moratorium on gain of function research in America. Dr. Anthony Fauci t...

The lies that rightist propaganda outlets train their ideological parrots to spew conflict with reality.

The Wuhan Lab and the Gain-of-Function Disagreement - FactCheck.org

A disagreement between Republican Sen. Rand Paul and Dr. Anthony Fauci has put $600,000 of U.S. grant money to the Wuhan Institute of Virology back into the spotlight, while making "gain-of-function" research a household term -- all amid calls for more investigation into the origins of SARS-CoV-2.

www.factcheck.org

The Facts – and Gaps – on the Origin of the Coronavirus - FactCheck.org

Despite increased media attention to the possibility that the novel coronavirus may have escaped from a lab, no credible evidence has emerged to support it and most scientists think the virus likely has a natural origin.

www.factcheck.org

If someone prefers to push the dogma of failed casino operators over data provided by public health experts in matters of public health, that is his right.

Most Americans are just not that silly.

Most Americans Now Support Mask And Vaccination Mandates.​

Most Americans Now Support Mask And Vaccination Mandates. Which Companies Will Follow Their Lead?

A new poll found that a majority of Americans say protecting the common good is more important than ensuring personal liberty when considering whether to require people to get a Covid-19 vaccination or wear a protective mask.

www.forbes.com

​

Unfortunately, some are, and incorrigibly so:

Supporters at Alabama rally boo Trump after he tells them to get vaccinated

​

 

[badger2]

But the bat-to-human rotavirus (Thailand, post #168) also links to two proven reservoirs of SARS-CoV:

Dec 2010 Japan / Nyctereutes-Paguma Rotavirus

Molecular characterization of rotaviruses in a Japanese raccoon dog (Nyctereutes procyonoides) and a masked palm civet (Paguma larvata) in Japan - PubMed

Group A rotaviruses infect and cause diarrhea in humans and a wide range of mammals. Previous studies have suggested that some strains can cross the species barrier to infect humans (Martella et al., 2010). However, there are few reports on infection and characterization of rotaviruses in wild...

Pubmed.ncbi.nlm.nih.gov

’....We detected rotaviruses in one sample from a Japanese raccoon dog (Nyctereutes procyonoides) (RACDG5) and in one masked palm civet (Paguma larvata) (MP-CIVET66) by RT-semi-nested PCR.’

 

[Lesh]

The lies that rightist propaganda outlets train their ideological parrots to spew conflict with reality.

The Wuhan Lab and the Gain-of-Function Disagreement - FactCheck.org

A disagreement between Republican Sen. Rand Paul and Dr. Anthony Fauci has put $600,000 of U.S. grant money to the Wuhan Institute of Virology back into the spotlight, while making "gain-of-function" research a household term -- all amid calls for more investigation into the origins of SARS-CoV-2.

www.factcheck.org

The Facts – and Gaps – on the Origin of the Coronavirus - FactCheck.org

Despite increased media attention to the possibility that the novel coronavirus may have escaped from a lab, no credible evidence has emerged to support it and most scientists think the virus likely has a natural origin.

www.factcheck.org

If someone prefers to push the dogma of failed casino operators over data provided by public health experts in matters of public health, that is his right.

Most Americans are just not that silly.

Most Americans Now Support Mask And Vaccination Mandates.​

Most Americans Now Support Mask And Vaccination Mandates. Which Companies Will Follow Their Lead?

A new poll found that a majority of Americans say protecting the common good is more important than ensuring personal liberty when considering whether to require people to get a Covid-19 vaccination or wear a protective mask.

www.forbes.com

​

Unfortunately, some are, and incorrigibly so:

Supporters at Alabama rally boo Trump after he tells them to get vaccinated
View attachment 529796

​

Alex Jones of course just went off on him

 

[schmidlap]

Alex Jones of course just went off on him

Alex Jones?

If he is a prominent, respected epidemiologist, virologist, or public health expert, his repute has somehow eluded me.

 

[danielpalos]

But the bat-to-human rotavirus (Thailand, post #168) also links to two proven reservoirs of SARS-CoV:

Dec 2010 Japan / Nyctereutes-Paguma Rotavirus

Molecular characterization of rotaviruses in a Japanese raccoon dog (Nyctereutes procyonoides) and a masked palm civet (Paguma larvata) in Japan - PubMed

Group A rotaviruses infect and cause diarrhea in humans and a wide range of mammals. Previous studies have suggested that some strains can cross the species barrier to infect humans (Martella et al., 2010). However, there are few reports on infection and characterization of rotaviruses in wild...

Pubmed.ncbi.nlm.nih.gov

’....We detected rotaviruses in one sample from a Japanese raccoon dog (Nyctereutes procyonoides) (RACDG5) and in one masked palm civet (Paguma larvata) (MP-CIVET66) by RT-semi-nested PCR.’

I make a motion to also research medicinal plants to help lower costs.

Traditionally blackberry leaf tea is used for a sore throat, sore gums or mouth ulcers. The leaves are high in Vitamin C and hydrolysable tannins and flavonoids. The astringent qualities of the tannins help to tonify mucosa. For this reason it’s also said to be useful for gastrointestinal inflammation and diarrhoea.

Galen, Greek physician to the Roman legions around 160 CE recommended that soldiers chew blackberry leaves for gum health and physical strength.

Homegrown Blackberry Leaf Tea — Windellama Organics

The deeply annoying wild blackberry canes are just starting to shoot up again around here, sending out purplish- green new growth. Having cut the canes right back to ground level in late autumn with a weed whacker, spring has sprung them into action. They’re especially

www.windellamaorganics.com

 

[badger2]

I make a motion to also research medicinal plants to help lower costs.

Traditionally blackberry leaf tea is used for a sore throat, sore gums or mouth ulcers. The leaves are high in Vitamin C and hydrolysable tannins and flavonoids. The astringent qualities of the tannins help to tonify mucosa. For this reason it’s also said to be useful for gastrointestinal inflammation and diarrhoea.

Galen, Greek physician to the Roman legions around 160 CE recommended that soldiers chew blackberry leaves for gum health and physical strength.

Homegrown Blackberry Leaf Tea — Windellama Organics

The deeply annoying wild blackberry canes are just starting to shoot up again around here, sending out purplish- green new growth. Having cut the canes right back to ground level in late autumn with a weed whacker, spring has sprung them into action. They’re especially

www.windellamaorganics.com

The James Duke database records hydroquinone from blackberry (Rubus). If PRRSV is SARS-CoV-2’s most ancient ancestor, then coming close is hydroquinone’s effect on swine pseudorabies, which has many of the symptoms (abortion, mummified fetus) of PRRSV:

Porcine Pseudorabies / Hydroquinone / Anti-Absorption / Anti-Internalization

Hydroquinone inhibits PRV infection in neurons in vitro and in vivo - PubMed

Pseudorabies virus (PRV) is a prevalent and endemic swine pathogen that causes significant economic losses in the global swine industry. Due to the emergence of PRV mutant strains in recent years, vaccines can't completely prevent and control PRV infection. Therefore, research and development of...

pubmed.ncbi.nlm.nih.gov

Pseudorabies

Pseudorabies - Wikipedia

en.wikipedia.org

If currently SARS-CoV-2’s closest relative came from a copper mine, hydroquinone links to antiviral activation by Cu2+:

Poliovirus RNA / Cu2+

The production of viral RNA inactivator(s) from the interaction of dihydric and trihydric phenols with cupric ion - PubMed

Eight lots of reagent-grade phenol from four companies were tested for capacity to interact with Cu2+ to produce an inactivator or inactivators of the transfective RNA obtained from poliovirions; such capacity to interact with Cu2+ is referred to as cofactor activity. Six of the lots showed...

pubmed.ncbi.nlm.nih.gov

’....The activity of hydroquinone was outstandingly high.’

Further linking pseudorabies with PRRSV is ivermectin:

Ivermectin: a systematic review from antiviral effects to COVID-19 complementary regimen - PubMed

Ivermectin proposes many potentials effects to treat a range of diseases, with its antimicrobial, antiviral, and anti-cancer properties as a wonder drug. It is highly effective against many microorganisms including some viruses. In this comprehensive systematic review, antiviral effects of...

pubmed.ncbi.nlm.nih.gov

 

[badger2]

Problematics include separation of hydroquinone from blackberry, followed by deliver to ACE2 receptor areas of the lungs in porcine and mouse models using an apparatus such as a vaporizer.

 

[basquebromance]

don't Fauci my Florida? really?

DON'T DESANTIS MY GRANDPARENTS!

 

[danielpalos]

The James Duke database records hydroquinone from blackberry (Rubus). If PRRSV is SARS-CoV-2’s most ancient ancestor, then coming close is hydroquinone’s effect on swine pseudorabies, which has many of the symptoms (abortion, mummified fetus) of PRRSV:

Porcine Pseudorabies / Hydroquinone / Anti-Absorption / Anti-Internalization

Hydroquinone inhibits PRV infection in neurons in vitro and in vivo - PubMed

Pseudorabies virus (PRV) is a prevalent and endemic swine pathogen that causes significant economic losses in the global swine industry. Due to the emergence of PRV mutant strains in recent years, vaccines can't completely prevent and control PRV infection. Therefore, research and development of...

pubmed.ncbi.nlm.nih.gov

Pseudorabies

Pseudorabies - Wikipedia

en.wikipedia.org

If currently SARS-CoV-2’s closest relative came from a copper mine, hydroquinone links to antiviral activation by Cu2+:

Poliovirus RNA / Cu2+

The production of viral RNA inactivator(s) from the interaction of dihydric and trihydric phenols with cupric ion - PubMed

Eight lots of reagent-grade phenol from four companies were tested for capacity to interact with Cu2+ to produce an inactivator or inactivators of the transfective RNA obtained from poliovirions; such capacity to interact with Cu2+ is referred to as cofactor activity. Six of the lots showed...

pubmed.ncbi.nlm.nih.gov

’....The activity of hydroquinone was outstandingly high.’

Further linking pseudorabies with PRRSV is ivermectin:

Ivermectin: a systematic review from antiviral effects to COVID-19 complementary regimen - PubMed

Ivermectin proposes many potentials effects to treat a range of diseases, with its antimicrobial, antiviral, and anti-cancer properties as a wonder drug. It is highly effective against many microorganisms including some viruses. In this comprehensive systematic review, antiviral effects of...

pubmed.ncbi.nlm.nih.gov

Although no specific treatment for acute infection with SuHV-1 is available, vaccination can alleviate clinical signs in pigs of certain ages.

 

[badger2]

Another naturally-occurring compound affects the Bartha strain of SuHV in the report from Buenos Aires:

SUHV Bartha

Antiviral activity of lambda-carrageenan prepared from red seaweed (Gigartina skottsbergii) against BoHV-1 and SuHV-1 - PubMed

The antiviral effect of polysaccharides has been known for many years. Carrageenans are considered a good alternative for the prevention of a wide range of diseases, mainly caused by enveloped viruses. The advantages lie on their high availability, low cost and low induction of resistance. The...

pubmed.ncbi.nlm.nih.gov

 

[badger2]

An auspicious sign, the reader will hit a paywall, though this study differentiates between SuHV and PRRSV:

Harbin, China: Division of Swine Infectious Diseases, State Key Laboratory / SuHV nanoPCR / Gene-Deleted Pseudorabies

A nanoparticle-assisted PCR assay to improve the sensitivity for rapid detection and differentiation of wild-type pseudorabies virus and gene-deleted vaccine strains - PubMed

Nanoparticle-assisted polymerase chain reaction (nanoPCR) is a novel method for the rapid amplification of DNA and has been adopted for the detection of virus because of its simplicity, rapidity, and specificity. A nanoPCR assay was developed to detect and differentiate wild-type and...

pubmed.ncbi.nlm.nih.gov

’....PRRSV....’

So, what gene is deleted to further distinguish between SuHV and potentially SARS-CoV-2’s most ancient ancestor?

 

[badger2]

It’s the PRV gE gene.

 

[badger2]

Next would be analysis of these amino acid sequences:

Glasgow, UK; Nanjing, China; Zhejiang University, Hangzhou, China; Institut Pasteur of Shanghai, Beijing, China / PRV

Interspecies Transmission, Genetic Diversity, and Evolutionary Dynamics of Pseudorabies Virus - PubMed

Our study provides important genetic insight into the interspecies transmission and evolution of PRV within and between different hosts that warrant additional surveillance.

pubmed.ncbi.nlm.nih.gov

’....Clade 2.2 (variant PRV) is currently the most prevalent genotype worldwide, and most commonly involved in cross-species transmission events (including humans)....we identified amino acid sites in some important glycoproteins gB, gC, gD, and gE, that may be associated with PRV adaption to new hosts and immune escape to vaccines.’

 

[badger2]

The above study also includes Free University, Berlin, Germany.

 

[schmidlap]

Americans are trusting public health professionals over crackpot politicians in matters of public health.

Most Americans support school mask, vaccine mandates, poll finds​

Most Americans support school mask, vaccine mandates, poll finds

As COVID-19 cases surge around the country, a majority of Americans say they support mask mandates for students and teachers in K-12 schools, according to a new poll, but their views are sharply di…

www.news10.com

​

 

[badger2]

Another PRRSV connection to wild pigs imported into North Carolina from Germany in 1912, this one also infects hunting dogs:

Jun 2012 Austria / SuHV-1 / Wild Boars

Detection and molecular characterization of Suid herpesvirus type 1 in Austrian wild boar and hunting dogs - PubMed

Aujeszky's disease (AD), caused by Suid herpesvirus type 1 (SuHV-1), is an economically important disease in domestic swine. Thus, rigorous control programmes have been implemented and consecutively AD in domestic swine was successfully eradicated in many countries, including Austria. However...

pubmed.ncbi.nlm.nih.gov

In humans, neuro-herpesvirus infection is usually fatal. Typical of the movement of HSV-1 in humans, Uniprot says of the gE (envelope glycoprotein) of SuHv-1: ‘In neuronal cells, gE is essential for anterograde spread of infection through the nervous system.’

 

[badger2]

Canine distemper (CDV) in raccoon dogs, a proven reservoir of SARS-CoV-2 links to maintaining both canine coronavirus and pseudorabies viruses in their labs. There is also phocine distemper in whales, dolphins and porpoises (Morbillivirus):

Aug 2017 Agricultural University of Hebei; Center for Inspection and Quarantine, Shiziazhuang, Hebei Province / Raccoon Dogs / CDV

Rapid and sensitive detection of canine distemper virus by real-time reverse transcription recombinase polymerase amplification - PubMed

The results demonstrated that the RT-RPA assay offers an alternative tool for simple, rapid, and reliable detection of CDV both in the laboratory and point-of-care facility, especially in the resource-limited settings.

pubmed.ncbi.nlm.nih.gov

’....CDV belongs to the family Paramyxoviridae of the genus Morbillivirus and is one of the most lethal infectious agents in both susceptible free-living and captive carnivores....canine distemper virus (CDV-FOX-TA strain, genotype: America-2), canine parvovirus, canine coronavirus (CCoV, ATCC VR-809), canine parainfluenza virus, pseudorabies virus (PRV, Barth-K61 strain) were maintained in our laboratory. All the dogs and raccoon dogs clinically were suspected of being CDV infected. Fifteen samples from the dogs and 5 samples from the raccoon dogs had been tested to be CDV positive....and 12 raccoon dogs from farms in Hebei Province, China, from 2014 to 2016.’

Hydroquinone from blackberry points to chloroquine and hydroxychloroquine against Amazonian leshmaniasis:

1971 Russia: Chlorine-Substituted Benzoquinine and Hydroquinine

[Study of antiviral effect of chlorine-substituted benzoquinine and hydroquinine] - PubMed

[Study of antiviral effect of chlorine-substituted benzoquinine and hydroquinine]

pubmed.ncbi.nlm.nih.gov

1970 Russia: Antiviral Activity of p-Benzoquinone and Hydroquinone Derivatives

[Antiviral activity of p-benzoquinone and hydroquinone derivatives] - PubMed

[Antiviral activity of p-benzoquinone and hydroquinone derivatives]

pubmed.ncbi.nlm.nih.gov

’....Similar Articles: Studies on Quinones. Part 39. Synthesis of Leishmanicidal Activity of Acylchloroquinones and Hydroquinones
2005 Santiago, Chile

Studies on quinones. Part 39: Synthesis and leishmanicidal activity of acylchloroquinones and hydroquinones - PubMed

Acylhydroquinone-based compounds are attractive targets for the design of new leishmanicidal drugs. We have previously described sesquiterpene quinones and hydroquinones series, which exhibit different degree of potency against Leishmania amazonensis. The present study details the preparation of...

pubmed.ncbi.nlm.nih.gov

’....The quinone or hydroquinone nucleus is essential for the activity of the members of this series.’

 

[badger2]

So anti-pseudorabies hydroquinone from blackberry (post #188) links to chloroquine/hydroxychloroquine via Leishmania amazonensis. Thus, with the origin hypothesis of Plagemann for PRRSV mentioned previously, LDV (lactate dehydrogenase-elevating arterivirus) is implicated:

Ap 2020 France: LDV Arterivirus Protective Effect In Malaria / Multiple Sclerosis / Cerebral Malaria

A Virus Hosted in Malaria-Infected Blood Protects against T Cell-Mediated Inflammatory Diseases by Impairing DC Function in a Type I IFN-Dependent Manner - PubMed

Coinfections shape immunity and influence the development of inflammatory diseases, resulting in detrimental or beneficial outcome. Coinfections with concurrent <i>Plasmodium</i> species can alter malaria clinical evolution, and malaria infection itself can modulate autoimmune reactions. Yet...

pubmed.ncbi.nlm.nih.gov

’The initial discovery of LDV arose within a few years in three different laboratories....In the first study, a massive increase in the level of lactate dehydrogenase was observed in the plasma of mice injeccted with 26 different transplantable tumors. In the second study, a moderate degree of splenomegaly and lymph node enlargement was noted in otherwise subclinically affected mice inoculated with material from wild mice. The third report noted interference with replication of vesicular stomatitis virus in infected mice. These characteristics — enzyme elevation, contamination of transplantable tumors, clinically silent infection with mild pathology, and immunomodulation — represent the primary reasons why LDV is a significant advventitious agent in the laboratory mouse.
....
The major factor in reducing virus titers in plasma during the early phase of infection is exhaustion of the target cell population, rather than any virus-specific immune response. Infection elicits a strong and specific immune response, but serum antibody and T-cell responses are not elicited in time to clear the high titers of replicating virus during the acute stage of infection, largely because the virus replicates so rapidly within the first few hours following infection.’
( Arterivirus Pathogenesis and Immune Response, in Nidoviruses ASM Press (2008) p. 332

The interference with vsv replication, above, links to the SARS-CoV-2 mutation Fau Chi gets backwards in his youtube video: D614G.