Big pharma companies sued over role in opioid crisis

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The suit, which DeWine said is the second by a U.S. state, after Mississippi, claims the drugmakers violated multiple state laws, including the Ohio Corrupt Practices Act, and committed Medicaid fraud.

Big Pharma Companies Sued Over Role in Opioid Crisis

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Ohio attorney general sues 5 pharma companies over their role in the opioid epidemic

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The video is really worth listening to , esp for those who hold the medical industry as their Gods of truth. It is amazing what they cover up, and the wordage used in order to deceive the average public person.

By learning even this little bit of information it can help be a tool for you to ask your own Doctors in certain aspects of your life and health.
 
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Just another revenue stream in an authoritarian predatory society.
 
In Wisconsin, it was the Tammy Baldwin scandal dealing with over-prescription of opioids in VA hospitals.
 
New York Times 6 Jun 2017 U.S. Drug Deaths Climbing Faster Than Ever
'....In Ohio, which filed a lawsuit last week accusing five drug companies of abetting the opioid epidemic, overdose deaths increased by more than 25 percent in 2016, according to the estimates...."July 5, 2016 -- that's the day that carfentanil hit the streets of Akron....It's sold on the street as heroin, or drug traffickers use it to make cheap counterfeit prescription opioids....an elephant tranquilizer 5,000 times stronger than heroin....that on three separate occasions the county had to request refrigerated trailers to store the bodies because they'd run out of space in the morgue....On that day, seventeen people overdosed and one person died in a span of nine hours.'
 
Carfentanil / Mu-Opioid Receptor
An updated synthesis of [11 C]carfentanil for positron emission tomography (PET) imaging of the μ-opioid receptor. - PubMed - NCBI
'[11C]carfentanil has been widely used for preclinical and clinical positron emission tomography (PET) imaging studies of the mu-opioid system since its introduction at Johns Hopkins University in the early 1980s.....suggests that the radiotracer binds preferentially to mu-opioid receptor subtype 1, compared to subtype 2. Our physician colleagues have used [11C]CFN to investigate the role of the mu-opioid system in tobacco smoking, obesity and weight loss, pain regulation as well as sex and genetic influences on these mechaisms,, social distress and reward, drug addiction and migraine, and treatment responses in major depression....more recently groups often methylate the precursor using [11C]MeOTf....this is critical because while other cartridges such as C8 and C18 trap [11C]CFN, they also retain significant quantities of desmethyl carfentanil precursor, which coelutes with [11C]CFN and contaminates the PET drug.'
 
Carfentanil Fatalities: Two Case Reports
Fatalities Involving Carfentanil and Furanyl Fentanyl: Two Case Reports. - PubMed - NCBI
'....Hillsborough County, Florida has seen an increase in illicit fentanyl and fentanyl analogs and heroin deaths with both categories nearly tripling from 2014 to 2016.....(N-phenyl-N-[1-(2-phenylethyl) 4-piperidinyl]propanamide)....first discovered in the heroin supply in 1979 in Orange County, California. Carfentanil (methyl-1(2-phenylethyl]-4-(N-propanylanilino) piperadine-4-carboxylate)....10,000 times greater than morphine 100 times greater than fentanyl....several does of naloxone may be required due to the unusually high potency of carfentanil.'

Note that the anilino moiety links with the binding of aniline dyes.
 
CDC says Some Doctors Still Prescribe Too Many Opioids...
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Some Doctors Still Prescribe Too Many Opioids, CDC Finds
July 6, 2017 - A report out today from the Centers for Disease Control and Prevention finds that use of these highly addictive narcotic pain meds dropped in the last few years. But a closer look at the numbers in the CDC study reveals another, more troubling trend: Some doctors are still overprescribing opioids, which puts lives at risk.
Overall, the use of OxyContin, Percocet, Vicodin, and other opioid pain medications decreased by 13 percent between 2012 and 2015. Yet even with that drop, prescribing remains alarmingly high, according to the CDC. In 2015, U.S. doctors prescribed enough opioids to medicate every American around the clock for three weeks. “The amount of opioids prescribed in the U.S. is still too high, with too many opioid prescriptions for too many days at too high a dosage,” said the CDC's acting director, Anne Schuchat, M.D.

Safer Pain Relief

Last year, the CDC released guidelines advising doctors to not prescribe more than three days' worth of opioids for most patients. “Healthcare providers have an important role in offering safer and more effective pain management while reducing risks of opioid addiction and overdose," Schuchat says. But because some doctors are too quick to prescribe opioids, patients need to speak up and ask about other options for relieving pain, advises Consumer Reports’ medical director, Orly Avitzur, M.D. "The thinking on opioid prescribing has changed in recent years as the severity of the risks of the drugs has come to light," Avitzur says. "We also have far more research supporting the effectiveness of safer medications and even nondrug measures."

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For example, research shows that the combination of over-the-counter acetaminophen (Tylenol and generic) and an anti-inflammatory drug such as ibuprofen (Advil, Motrin IB and generic) or naproxen (Aleve and generic) can actually work better than an opioid to relieve pain after a dental procedure. And the American College of Physicians now recommends avoiding opioids for most cases of back pain. Instead, the APC recommends trying nondrug options such as heat, acupuncture, massage, spinal manipulation, and yoga before resorting to any medication.

However, that updated advice can be slow to trickle down to all doctors' everyday practices, Avitzur says: "Prescribing habits become deeply entrenched. So it's important to remind your healthcare providers that you don't want—or need—a lengthy opioid prescription." Longer courses and higher doses of opioids are appropriate for people suffering severe pain from cancer or a terminal illness, she says. "But even after surgery or an injury, most other patients can transition to safer OTC pain relievers within three days, says Avitzur. "Very few patients need powerful prescription painkillers for more than a week."

Editor's Note: These materials were made possible by a grant from the state Attorney General Consumer and Prescriber Education Grant Program, which is funded by a multistate settlement of consumer fraud claims regarding the marketing of the prescription drug Neurontin (gabapentin).

Some Doctors Still Prescribe Too Many Opioids, CDC Finds

See also:

U.S. FDA asks Endo to withdraw Opana ER opioid; shares fall
Thu Jun 8, 2017 | The U.S. Food and Drug Administration said on Thursday it has asked Endo International Plc to withdraw from the market its long-lasting opioid painkiller Opana ER, sending the company's shares down more than 12 percent.
"After careful consideration, the agency is seeking removal based on its concern that the benefits of the drug may no longer outweigh its risks," the agency said in a statement. The move comes after a panel of advisers concluded in March that the benefits of Opana ER, which was approved in 2006 and reformulated in 2012 to resist abuse, did not outweigh the risks. While nasal abuse rates fell, the rate of intravenous abuse increased.

The withdrawal marks the first time the agency taken steps to remove an opioid pain medication due to the public health implications and comes amid an intense national debate about the abuse of opioids. Opioids were involved in more than 33,000 deaths in 2015 and opioid overdoses have quadrupled since 1999, according to the Centers for Disease Control and Prevention. "We are facing an opioid epidemic - a public health crisis, and we must take all necessary steps to reduce the scope of opioid misuse and abuse," Dr. Scott Gottlieb, the FDA's newly appointed commissioner said in a statement.

Opana ER has also been associated with a serious outbreak of HIV and hepatitis C, the agency said, as well as a serious blood disorder known as thrombotic microangiopathy. The move coincides with a lawsuit filed on May 31 against the pharmaceutical industry by Ohio, charging that a number of companies, including Endo, Purdue Pharma, Teva Pharmaceutical Industries Ltd, Johnson & Johnson and Allergan Plc conducted misleading marketing campaigns that downplayed the drugs' addictiveness. Some other states and cities have filed similar lawsuits.

Gottlieb said the agency will "continue to take regulatory steps when we see situations where an opioid product's risks outweigh its benefits, not only for its intended patient population but also in regard to its potential for misuse and abuse." Endo's shares fell 12.2 percent to $12.10 in extended trading.

U.S. FDA asks Endo to withdraw Opana ER opioid; shares fall
 
Rich drug panderer busted in opioid scheme...
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Billionaire pharma founder busted in opioid scheme
October 26, 2017 - The billionaire founder of Insys Therapeutics was arrested on Thursday on US charges that he participated in a scheme with other executives to bribe doctors to prescribe a fentanyl-based cancer pain drug and to defraud insurers.
John Kapoor, 74, who stepped down as chief executive of Insys in January, was charged with having engaged in conspiracies to commit racketeering, mail fraud and wire fraud in an indictment filed in federal court in Boston. He was arrested in Arizona, where Insys is based, and added as a defendant in a previously filed case against six former Insys executives and managers, including former Chief Executive Michael Babich, prosecutors said. Brian Kelly, Kapoor’s lawyer, said in an email: “My client is innocent and he intends to fight these charges vigorously.”

Insys, which has been in settlement talks with the US Justice Department in connection with the probe, declined to comment. Its stock price fell more than 20 percent to $5.92 in midafternoon trading on Thursday. The charges marked a major escalation of the ongoing investigations of Insys related to Subsys, an under-the-tongue spray that contains fentanyl, a highly addictive synthetic opioid.

Those probes have come amid a national opioid abuse epidemic. According to the US Centers for Disease Control and Prevention, opioids were involved in over 33,000 deaths in 2015. The death rate has continued to rise, according to estimates. Kapoor, who founded Insys in 2002 and remains a board member, stepped down in January as the company’s chairman and chief executive, a role he took on in November 2015. He is currently the chairman of drugmaker Akorn and president of investment firm EJ Financial Enterprises.

According to the indictment, following the launch of Subsys in 2012, Kapoor and Babich grew dissatisfied with the drug’s success in its initial three months on the market. It says they, with others, devised a scheme to pay bribes in the form of speaker fees and food and entertainment to medical practitioners to prescribe Subsys and to increase the dosage and volume of existing prescriptions. They also sought to mislead and defraud insurers who were reluctant to approve payment for Subsys when it was prescribed to patients who did not have cancer, the indictment said.

http://nypost.com/2017/10/26/billionaire-pharma-founder-arrested-in-us-opioid-scheme/
 
Folks, are dangerous, addictive opiods covered by insurance but not Cialis? A wonder drug. WTF? Congress needs to investigate why that is happening.
 
The company that makes a drug is not responsible for the misuse of that drug.

After I had surgery I was prescribed opiates any my insurance company would only approve 30 doses at a time.
 



The suit, which DeWine said is the second by a U.S. state, after Mississippi, claims the drugmakers violated multiple state laws, including the Ohio Corrupt Practices Act, and committed Medicaid fraud.

Big Pharma Companies Sued Over Role in Opioid Crisis

View attachment 130897

Ohio attorney general sues 5 pharma companies over their role in the opioid epidemic

------------------------------------------------------------------------------------------------------------------

The video is really worth listening to , esp for those who hold the medical industry as their Gods of truth. It is amazing what they cover up, and the wordage used in order to deceive the average public person.

By learning even this little bit of information it can help be a tool for you to ask your own Doctors in certain aspects of your life and health.

break the law go to jail.

unless you donate to the government, then you just get sued for 1/2 the profit you made and come up with something else.
 
The company that makes a drug is not responsible for the misuse of that drug.

After I had surgery I was prescribed opiates any my insurance company would only approve 30 doses at a time.
they broke the law, the lawyers are just pandering to the media for support as they will become 1%ers should they win
 
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