When I first saw the headline I rolled my eyes, but as I read it I became horridly fascinated. The basis for the author's prediction is the the seemingly predictable cycles in both party's presidential nominations, which would seem to indicate Santorum will win the Republican nomination and defeat whoever the Democrats nominate.
Make of it what you will.
First of all, I've met the guy and I don't think Santorum is capable.
Then you have to consider he lost a Senate re-election campaign by 18 points.
Meh, not so much. He lost against a very conservative Democratic opponent in a year when having an R behind your name was a death sentence.
Mitt Romney didn't even TRY to run for re-election in 2006.
If Santorum could unite the religious and TEA party wings of the GOP, he could get the nomination.
As for winning in the general, that would depend entirely on economic conditions.
I do think the next GOP nominee needs to be someone like Santorum- someone from a working class background who doesn't say dumb shit like "I'm not concerned about the very poor" and "I like to be able to fire people".