Here are a similar set of images from the same source that have the dates actually marked on them. Nice pictures, but you failed to address anything I said. See text below these four images.
So, almost no Atlantic Ocean, massive Pacific, Australia just separated from Antarctica, North Africa and half of Europe underwater, North and South America disconnected, the Indian subcontinent just beginning its collision with Asia, raising the Himalayas, Asia and Southeast Asia still united. You don't think these differences might have dramatically affected ocean circulation?
I assume what you meant to say was "...since you are claiming that elevated CO2 levels today (which are 2 to 3 times less than in the past) will cause temperatures to rise today.".
[Feel free to gaff me for being the language police, but I have always disliked the construction "2 to 3 times less" because it really makes no sense. Either say that levels in the past were 2 to 3 times higher or that today's levels are one-half to one-third past levels.]
Here are a couple of points to ponder.
1) The cooling since the Paleo-Eocene Thermal Maximum has taken 50 million years. The warming mainstream science attributes to rising anthropogenic CO2 has taken place over 150 years (and most in the last 50), 3 ten-thousandths of one percent of that time span at almost 400 million times the rate. That makes any attempt to equate or analogize the processes responsible for those changes dubious at best.
2) The tectonic changes of the last 50 million years ARE significant, particularly in terms of ocean circulation and the amount of exposed landmass in each hemisphere. I have no problem with the expert's opinion that it is those tectonics shifts that are responsible for the long term cooling since the PETM. Your contention that the plate configurations "aren't much different" seems to me nothing but an out of hand rejection with no thought given to the question at all.
3) Mainstream science has always considered a number of different positive and negative forcing factors to be responsible for global temperature changes. CO2 is considered the primary factor for the CURRENT warming. It is not claimed to be the primary factor for ALL warming throughout Earth history.