I know it's light years away, but I'm doing a dead pool. There always has to be major characters killed off. My guess is Carol and Herschel.
Foresure Living (90%>)
Rick (main protagonist), Carl (just don't see him going), Daryl (fan favorite), Michonne (she is a savior in the comic, I think they will keep it that way), Judith (they don't kill babies on TV)
More like to live than die: (50%-90%)
Tyreese (I think they got the hint to not kill off Black characters one after another), Glenn and Maggie (the power couple), Beth (in the comic Sophia is suppose to be a savior and hasn't died yet and Beth died early on - I believe they flipped these two and I think they will try to make her a love interest of Carl)
More likely to Die than live (25-90%)
Sasha (I have a feeling they'll knock her off), Martinez (for some reason he stuck with the Gov, there could be a chance he abandons the Gov and some how lives); Roy Stark (mentioned as a new major character. I think he will be a goner like the major characters added like Axel, Oscar and Merle)
Foreshure Dead (<10%)
Herschel and Carol (they need to kill main characters - Jim, Andrea's Sister, the Black Lady and Carol's husband season one; Shane, The Guy with the Fish Hat, Sophia season 2; Andrea, TDogg, Axel, Oscar, Merle season three), Shupert (This was the Black right hand man of the Gov - He didn't have many lines and I think he dies early); Karen (the girl that played dead to escape the Gov - Yea she is a goner); Gov (He was supposed to be in only one season, but people loved to hate him - he will be back, but won't make it to a 3rd); - Countless Woodbury Refugees (they were brought in to become Walker Food and Gov target practice).
Chances of Morgan coming back: 10%. Seems like an awesome character and a great actor. He was also a major character from the comic, yet they don't seem to want to bring him back.
Chances of Morales Family Making a Comeback: 20%. This family left for greener pastures in the first season. Could they come back? Maybe the Mom with the kids. Pappa Morales without his family (ironic since he left to find more family members). I think they could possibly bring them back.