106 of the first 108 colleges were started on the Christian faith. By the close of 1860 there were 246 colleges in America. Seventeen of these were state institutions; almost every other one was founded by Christian denominations or by individuals who avowed a religious purpose.
Harvard College, 1636 - An Original Rule of Harvard College: "Let every student be plainly instructed and earnestly pressed to consider well, the main end of his life and studies is, to know God and Jesus Christ which is eternal life, (John 17:3), and therefore to lay Christ in the bottom, as the only foundation of all sound knowledge and learning."
William and Mary, 1691 - The College of William and Mary was started mainly due to the efforts of Rev. James Blair in order, according to its charter of 1691, "that the Church of Virginia may be furnished with a seminary of ministers of the gospel, and that the youth may be piously educated in good letters and manners, and that the Christian religion may be propagated among the Western Indians to the glory of Almighty God."
Yale University, 1701 - Yale University was started by Congregational ministers in 1701,"for the liberal and religious education of suitable youth…to propagate in this wilderness, the blessed reformed Protestant religion…"
Princeton, 1746 - Associated with the Great Awakening, Princeton was founded by the Presbyterians in 1746. Rev. Jonathan Dickinson became its first president, declaring, "cursed be all that learning that is contrary to the cross of Christ."
University of Pennsylvania, 1751 - Ben Franklin had much to do with the beginning of the University of Pennsylvania. It was not started by a denomination, but its laws reflect its Christian character. Consider the first two Laws, relating to Moral Conduct (from 1801): "1. None of the students or scholars, belonging to this seminary, shall make use of any indecent or immoral language: whether it consist in immodest expressions; in cursing and swearing; or in exclamations which introduce the name of God, without reverence, and without necessity. "2. None of them shall, without a good and sufficient reason, be absent from school, or late in his attendance; more particularly at the time of prayers, and of the reading of the Holy Scriptures."
Some other colleges started before America's Independence include: Columbia founded in 1754 (called King's College up until 1784), Dartmouth ,1770; Brown started by the Baptists in 1764; Rutgers, 1766, by the Dutch Reformed Church; Washington and Lee, 1749; and Hampton-Sydney, 1776, by the Presbyterians.
History of America's Education #3 Universities, Textbooks and Our Founders