100,000 years ago -
Homo sapiens arrives in the Middle East.
110,000 years ago - Beginning of the most recent
glacial period: the
Wisconsin glaciation.
130,000 years ago - Beginning of the
Eemian interglacial.
200,000 years ago - Beginning of the 2nd most recent
glacial period: the
Wolstonian glaciation.
250,000 years ago - First
Homo sapiens.
350,000 years ago - First
Homo neanderthalensis.
380,000 years ago - Beginning of the
Hoxnian interglacial.
450,000 years ago - Beginning of the 3rd most recent glacial period: the
Kansan glaciation, during which ice sheets reached their maximum extent in the
Pleistocene, down to Kansas and Slovakia.