what has any of that got to do with pot and Colorado?
That's probably the most random, off-the-wall reply I've ever seen.
The state is defying federal law in the matter, based on the will of their citizens.
Alabama should do the same if the Supreme Court has a moment of insanity and says the people are not sovereign.
And if the Federal government wants to it can either:
a) file suit against Colorado, as it did against Arizona or
b) send DEA agents in and arrest pot growers.
Alabama will no more prevent gay marriages than it prevented mixed race marriages when the Court told the people of Alabama that their state laws are subject to the Constitution also.