If you are a virologist or have detailed knowledge about the various Covid-19 vaccines, then please answer this question. If you do not have detailed knowledge, kindly refrain from responding to this thread.
Given that the Pfizer vaccine is showing over 80% efficacy after one dose (CDC report), J&J vaccine is about 70% effective and is delivered as a single dose
why is the Pfizer vaccine STILL being pushed as a two dose vaccine with so many people still waiting for their first shot of any vaccine?
We asked UCSF infectious disease expert Monica Gandhi, MD, MPH, to unpack some of the big questions around vaccine science, such as how the Johnson & Johnson vaccine differs, how well it works against the new variants, and whether you should be worried about transmitting the virus after vaccination.
www.ucsf.edu
Both Pfizer and Moderna (Biontech) vaccines are BRAND NEW technology.. They do not rely on the time tested method of using "killed virus" or "vector host" vaccine that in one way or the other introduces a benign version of the actual target virus..
Instead they use the body to create antibodies based on introducing a "messenger RNA" for a PIECE of the virus. The body then "learns" how to destroy virus from a totally MAN-MADE snippet of the virus DNA..
The 2 shot recommendation was to avoid OVERLOADED reactions by the body to produce the antibodies and start fighting the stuff RECENTLY injected. So -- there is that 2 week or 3 week period to cool off the body reaction in between. And at the 2nd shot -- you are ASKED for adverse symptoms from the FIRST injection..
Was REALLY REALLY BALLSY to haul this out of academic theory and apply it to humans on an emergency basis. But there was some genetically modified" animal tests done where the animal has a "human-like" immunity response in place before the authorization and clinical trials..
With all that said -- a couple countries (France and maybe one/two others) are pondering or enacted a path to using these mRNA vaccines ON a one shot basis. Check the news for that. And Fauci (usually wrong at first) made some noise today about the needs for "booster shots".. Because NO ONE actually knows the endurance of the immunity that ANY of these vaccines will provide against prime variants and CV-19...
DO we know which vaccines are reported to have the most adverse reactions, if I understand from what your saying correctly, it would be the single shot vaccine, right?
All of them have REPORTED instances. The problem is whether there's evidence the reports have anything to do AT ALL with the vaccines. And there's reason to be skeptical about the "blood clot" issues with Astra-Zenica because they are the "odd man out" and the "late bird". And the market is now SATURATED with CV-19 vaccine makers who are NERVOUS about new-comers, because their "time to shine" on this payback is so short.
There are even reported deaths.. But the number is tiny and not totally attributed to any vaccine..
It's a weird business of getting drugs to market. All those "side effects" you hear about on commercials are NOT PROVEN TO BE LINKED to the drug in most all cases.. The GOVT requires that ANY adverse reaction be included in the possibilities even without PROOF of a connection to that drug.
So when you make a vaccine to PRIMARILY keep the elderly from dying -- you're dealing with a drug company nightmare when your target customers are elderly and in bad health and must be statistically and realistically sampled during your trials.. Because there WILL BE reports..
Bottom line -- UNFORTUNATELY -- this weird system takes DECADES sometimes to resolve AFTER the drug hits the marketplace. Then lawyers ultimately argue these cases for another decade before the COURTS ultimately decide if the warnings were "inadequate"..
You wont be around to see any money from this if anything goes wrong.. So -- just roll up your sleeve and do it on "faith"... LOL....
