Hillary was into politics nearly before she knew how to use the toilet herself. From Wiki biography:
She saw evidence of
electoral fraud (such as voting list entries showing addresses that were empty lots) against
Republican candidate
Richard Nixon,
[22] and later volunteered to campaign for Republican candidate
Barry Goldwater in the
U.S. presidential election of 1964.
[23] Rodham's early political development was shaped most by her high school history teacher (like her father, a fervent
anti-communist), who introduced her to Goldwater's
The Conscience of a Conservative and by her
Methodist youth minister (like her mother, concerned with issues of
social justice), with whom she saw and afterwards briefly met,
civil rights leader
Martin Luther King Jr. at a 1962 speech in Chicago's
Orchestra Hall.
[24]
From there she never stopped, so you can't tell me she had no intention of political calculations long before she was first lady.