Yes, there are Old Testament prophetic scriptures that talk about the Messiah being rejected by His own people. Two that immediately come to mind, are these:
Psalm 118:22
The stone which the builders rejected
Has become the chief cornerstone.
Isaiah 53:3
He is despised and rejected by men,
A Man of sorrows and acquainted with grief.
And we hid, as it were, our faces from Him;
He was despised, and we did not esteem Him.
And there are other scriptures that talk about how the Jewish people were blinded, a spiritual blindness....but that blindness will be lifted in the end.