It is the first time that anyone has tried to correct a genetic defect in the light-sensing cells that line the back of the eye. The president of the Academy of Medical Sciences said the widespread use of gene therapy of this treatment will be soon be possible. The operation was carried out on 63-year-old Jonathan Wyatt, an arbitration lawyer based in Bristol. Mr Wyatt was able to see normally until about the age of 19 when he began having problems seeing in the dark. He was told by doctors that his vision would get progressively worse and he would eventually go blind.
The gradual deterioration in his vision didn't stop Mr Wyatt from qualifying as a barrister. But 10 years ago he found he was having difficulty reading statements in dimly-lit courts. "The worst occasion was when I was reading out a statement to the court and I made a mistake. The judge turned to me and snapped 'Can't you read Mr Wyatt?!' I then decided it was time to put my wig down and leave advocacy." Geneticist Dan Lipinski, from the University of Oxford, explains the gene therapy process
Mr Wyatt is able to see well enough to work from home and hopes that the operation will enable him to continue his profession. Without treatment he would be blind within a few years and would be unable to work in the way that he is doing so now. "I'd like things to get a little better," he says.
Devastating diagnosis