Disir
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- Sep 30, 2011
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The researchers concluded that the combination of mmRNA encoding Stemin and YAP-5SA is a promising treatment for human heart disease.
When asked about the study’s limitations, Dinakar Iyer of the Department of Biology and Biochemistry at the University of Houston, one of the study’s authors, told MNT: “The major limitation is that our study findings are limited to only mice. We are planning to repeat the same experiments in pigs and see if we could get a similar response. If the outcome is similar in pigs, our next approach will be to do a limited study (with FDA approval) in heart patients.”
Dr. Schwartz added, “It is possible that the mRNA combination may not work in human patients, but because the genetic pathways that are activated by our mRNA combination are very similar in all mammals, we are confident that they will work in humans as well.”
www.medicalnewstoday.com
That's an interesting study as long as the limitations are kept in mind.
When asked about the study’s limitations, Dinakar Iyer of the Department of Biology and Biochemistry at the University of Houston, one of the study’s authors, told MNT: “The major limitation is that our study findings are limited to only mice. We are planning to repeat the same experiments in pigs and see if we could get a similar response. If the outcome is similar in pigs, our next approach will be to do a limited study (with FDA approval) in heart patients.”
Dr. Schwartz added, “It is possible that the mRNA combination may not work in human patients, but because the genetic pathways that are activated by our mRNA combination are very similar in all mammals, we are confident that they will work in humans as well.”
Experimental treatment repairs cells after heart attack
In a mice study, researchers developed an experimental treatment that can repair and regenerate heart muscle cells following a heart attack.
www.medicalnewstoday.com
That's an interesting study as long as the limitations are kept in mind.
