Amino Acids: The Building Blocks of Life
Putting it kindly, orogenicman's imagination knows no bounds!
Below I address the contents of each of the articles and the peer-reviewed paper at the other end of
orogenicman's links. Directly below each of the pertinent excerpts, the reader will find my notes. Please be patient and carefully think about the material as you read 'til you get to the end. As a matter of clarification owing to the ultimate concern, there's a reason why I have consistently used the phrase
exist/persist in nature in this thread above
orogenicman's latest stunt. Remember, in this OP, the issue is the metaphysics of evolutionary theory. And in this instance, chemical evolution (i.e., abiogenesis) is the issue relative to
orogenicman's outlandish claims about the amino acids that are synthesized in the interstellar and Earth-bound laboratories of the cosmos—under both natural and controlled environments/conditions.
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(
Abiogenesis: The Unholy Grail of Atheism by Michael David Rawlings at
Prufrock's Lair)
Bear in mind the 6 durable and commonly found amino acids as you read: glycine, alanine, glutamic acid, aspartic acid, valine and proline.
Link #1
Pertinent excerpt: "One of the newly-discovered molecules, called
E-cyanomethanimine (E-HNCHCN) is one step in the process that chemists believe produces
adenine, one of the four nucleobases that form the “rungs” in the ladder-like structure of DNA. The other molecule, called
ethanamine, is thought to play a role in forming
alanine, one of the twenty amino acids in the genetic code."
Note: Though we're jumping ahead of the amino acids here, cyanomethanimine is believed to be one of the catalysts for adenine. However, the synthesis for adenine also requires
(1) cyanoacetylene (or its hydrolyzed form
cyanoacetaldehyde) and/or
(2) the anion
cyanate.
Cyanoacetylene is a plentiful organic compound in the universe, but it's highly reactive with other chemicals or compounds, especially in its hydrolyzed form.
Cyanate is derived from the hydrolysis of cyanogen, which has an estimated half-life of less than 30 seconds on Earth beyond laboratory conditions.
Alanine, of course, is one of the
6 durable amino acids of life commonly found in nature, albeit, in racemic mixtures outside of living cells. Nothing new here.
Check?
Link #2
Pertinent excerpt: "With only about 100 billionths of a gram of
glycine to study, the researchers were able to measure the relative abundance of its carbon isotopes. It contained more carbon-13 than that found in
glycine that forms on Earth, proving that Stardust's glycine originated in space."
Note: Glycine, of course, is one of the
6 amino acids of life commonly found in nature outside living organisms, albeit, in racemic mixtures. Nothing new here either, except what had long been suspected: all glycine, being the simplest and, therefore, the sturdiest of life's amino acids, with only two hydrogen atoms on its side chain, may have originated in space. I touch on this in my article at
Prufrock's Lair. This is probably true about the durable amino acids
alanine and
glutamic acid as well.
Check?
Link #3
Pertinent excerpt: "A new experiment simulating conditions in deep space reveals that the complex building blocks of life could have been created on icy interplanetary dust and then carried to Earth, jump-starting life.
. . . In the new experiment, a vacuum chamber chilled to 10 degrees above absolute zero was used to house a mix of ice, carbon dioxide, ammonia, and various hydrocarbons such as methane, ethane, and propane. When zapped with high-energy electrons to simulate cosmic rays in space, the chemicals reacted to form complex, organic compounds.
. . . The analysis revealed the presence of complex molecules –
nine different amino acids and at least two dipeptides. . . ."
Note: The dipeptides synthesized were
Gly-Gly (
glycine-glycine) and
Leu-Ala (
leucine-alanine). This detail was not included in the article cited by
orogenicman.
In addition to the more durable
6 that commonly occur in nature and in the experimental apparatuses of synthesization, this is one of the potential ways that perhaps a few of the more fragile amino acids of life might be found in nature outside living organisms, albeit, always in racemic mixtures: that is to say, as chemically bonded to one of the durables or isolated in encapsulated deposits, thusly protected soon after the moment of synthesis from further chemical reactions or denaturation. Typically, they cannot maintain their composition in nature otherwise for any realistically useful period of time, except perhaps the semi-durable leucine, which is occasionally found in meteorites on Earth. In fact, leucine is sometimes counted as the
seventh amino acid of life commonly found in nature, though it appears in significantly smaller concentrations than the other
6 in both nature and in the experimental apparatuses of synthesization. Also, isoleucine was found in the Murchison Meteorite (See below.).
Check?
Link #4
Pertinent excerpt: "The discovery of
glycine in space suggests that interstellar molecules may have played a pivotal role in the prebiotic chemistry of the Earth."
Note: Ya think? Of course! Again, glycine is one of the
6 durable amino acids of life commonly found in nature, albeit, in racemic mixtures outside of living cells. Nothing new here either, though in the minds of atheists, the perbiotic chemistry that subsequently takes place on Earth from precursor to life . . . well, you know, nature did it! . . . all by itself.
Check?
Link #5
Pertinent excerpt: "The meteorite in question was born in a violent crash, and eventually crashed into northern Sudan.
. . . Life on Earth uses left-handed amino acids, and they are never mixed with right-handed ones, but the amino acids found in the meteorite had equal amounts of the left- and right-handed varieties."
Note: In other words, they're of a racemic mixture, which is always the case in nature outside of living cells. By the way, among the amino acids found in the Sudanese Meteorite were the
6 durables of life commonly found in nature—glycine, alanine, glutamic acid, aspartic acid, valine and proline. Of course, none of the other
14 that occur in life were present, except, perhaps, leucine and isoleucine, either as chemically bonded to one of the durables or isolated in encapsulated deposits. However, I don't remember if the later were found in this meteorite or not.
Check?
Link #6::
Amino acids in meteorites, Cronin JR, Pizzarello S.; Adv Space Res.;
1983;3(9):5-18.
Pertinent excerpt: "Eight of the terrestrial protein amino acids have been found."
Note: Psst,
orogenicman, did you not notice that when you posted the link? That's
8 of the
20,
orogenicman, not
17 of the
20!
Now carefully read on and try to understand this time. . . .
Actually, this paper is dated.
10 of life's amino acids have been found in the Murchison Meteorite: the
6 durables, leucine, and also isoleucine, serine and threonine. Altogether,
92 different amino acids of the
500 known have been found in the Murchison. Of course, except for the
10 biotic amino acids found in the Murchison, the rest are abiotic. Of the
92, only
19 are also found on Earth.
Now, for the ones found in the Murchison that matter to life:
1. The standard 6, the most durable and commonly found in nature.
2. Leucine.
3. Isoleucine, Serine and Threonine.
Serine and threonine are known terrestrial contaminants that can maintain the integrity of their composition on Earth as long as they are encapsulated almost immediately. The environmental conditions have to be just right. Naturally, they're deposited by living organisms; hence, they don't count and were found in the Murchison in trace amounts. They simply weren't detected for years. We now have the technology to see it all. Isoleucine may also be a terrestrial contaminant. To my knowledge, it's only been found in the Murchison in trace amounts. For some, the jury is still out on that one, but like leucine, it's a semi-durable, so it might be legit.
Notwithstanding, as I cited from my article at
Prufrock's Lair in the above, "[d]ue to the barely measurable presence and woeful instability of the other 11 [synthesized in experimental apparatuses], no one of any repute would have the temerity to argue that they could have existed in any significant concentrations in the primordial world beyond the environment of a living cell."
The issue here is abiogenesis! The problem with leucine and isoleucine is that they only show up in comparatively trace amounts in the experimental apparatuses of synthesization or in space debris. While geologists make a lot of hay over them, the leading lights of abiogenetic research know better. Though semi-durable, they are still more highly reactive and more subject to the forces of denaturation outside of living organisms or encapsulated deposits.
On the other hand, the standard, more durable
6 are always present in greater concentrations in the experimental apparatuses of synthesization and commonly occur in nature: inside and outside of living organisms on Earth, or inside the planetoids, asteroids, meteorites, comets, space clouds/nebulae of outer space. Of these
6, the simplest and, therefore, the most durable and common are glycine and alanine.
Bottom line: vast amounts of usefully stable organic material would be required for the processes of an abiogenetic mechanism of origin on Earth, where all things would have had to come together regardless of where the precursors were "born"—an environment rife with cross-containments and other factors incessantly pushing against the tide of the conservation of indispensable chemical information, obstacles that are not present in the dramatically more pristine conditions of space or in those of the controlled laboratories on Earth.
And here I'm speaking objectively, as the mathematical probabilities of abiogenesis (given not only the staggering problem of concentration, but at least six other, impenetrably major problems) are astronomical.
So why do the proponents of abiogenesis go on asserting this hypothesis as an assumptive fact? It's as simple as this: we're here, so it must have happened just so! The apparent necessity or potentiality of intelligent design must not be allowed even a hint of a foothold . . . or else the entire apparatus of evolutionary origins premised on metaphysical naturalism collapses.
Nature did it!
The fact of the matter is that until recently most of the leading lights of abiogenetic research, those who do or have done the real grunt work of organic synthesis, including Miller, talk about the prospects of abiogenesis in a dramatically more hushed and sober tone.
Check?
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In any event, orogenicman, we're still waiting for that link of yours that would back your ridiculous claim that all 17 of life's amino acids that can be synthesized under the controlled conditions of the laboratory are commonly found in nature.
Are you finally ready to move on to the actualities of "the purines and pyrimidines used in nucleic acid synthesis" in nature outside of living organisms and the experimental apparatuses of synthesization?
Any interest yet in facing up to the unfettered realities of their polymerization on Earth? How about facing up to the actualities of their indispensable precursors under the unfettered conditions of nature?