Again,
candycorn has it right, but accepting the OP's premise as we must since DeSantis announced:
DeSantis has to make up his mind what version of himself he will run as.
Is he Trump-without-the-negatives? That won't sit well with Trumpers. Especially now since so many of Trump's negatives have been proven to be Hillary-funded hoaxes. He or his surrogates would have to be out front talking about Trump's negatives that are based on reality, putting him in a position of running a negative campaign that will help the Dems if Trump wins the nom.
Is he Ron "Donald who?" DeSantis, only talking about himself without reference to or comparison with Trump? That would be the best strategy for the unlikely but definitely possible event that Trump dies or becomes incapacitated during the primary season. It is also the easiest strategy since he wouldn't have to measure his words when talking about Trump. He'll have to practice answering questions about Trump by talking about himself, since the MSM won't ask him anything but quesions about Trump.
Is he the guy who will actually do what Trump promised but did not do? His record of bussing illegals to sanctuary cities makes that a plausible claim.
EDIT: So does the list posted by
YoursTruly. Easy to imagine President DeSantis ordering the military to build the wall and letting any objections play out in court. That is the strategy that will bring out the worst street brawler in Trump, so DeSantis would have to be ready.
Is he running for president, but really running for VP? That would be the best strategy politically, given his age and inexperience in the executive branch. That would also be the hardest to pull off. Nikki Haley and Tim Scott are far more likely to succeed in that strategy. The GOP cannot keep running white male only tickets and expect to win.