New drug offers “two-for-one” treatment of heart failure, sleep apnea

[Jessica-stormlover]

New drug offers “two-for-one” treatment of heart failure, sleep apnea
By Paul McClure
March 30, 2023

New drug offers “two-for-one” treatment of heart failure, sleep apnea

Heart failure is a global health problem commonly complicated by sleep apnea, a co-morbidity that further reduces a person’s lifespan. A promising new drug has been developed that could treat heart failure and sleep apnea by targeting the nervous activity that drives both.

newatlas.com

Heart failure is a global health problem commonly complicated by sleep apnea, a co-morbidity that further reduces a person’s lifespan. A promising new drug has been developed that could treat heart failure and sleep apnea by targeting the nervous activity that drives both.

For people with heart failure, the prognosis is poor and mortality high despite recent advances in treatment. According to the National Institutes of Health, heart failure affects more than 64 million people worldwide, making it a major global public health priority.

Heart failure occurs when the heart muscle weakens and doesn’t pump effectively. The brain responds to heart failure by activating the body’s sympathetic nervous system, the “fight or flight” response, to stimulate the heart to pump more effectively. However, long-term stimulation over the long term, combined with sleep apnea, leads to a reduced life expectancy. Most patients die within five years of a diagnosis of heart failure.

The part of the brain that sends impulses to the heart also controls breathing. Central sleep apnea (CSA) – where breathing repeatedly stops during sleep because the brain doesn’t send proper signals to the respiratory muscles – is common in people with heart failure. Sleep apnea is thought to be caused by increased sensitivity in the peripheral chemoreceptors found in the carotid arteries, which detect changes in arterial blood oxygen (hypoxia) and initiate reflexes to return oxygen levels to normal. One receptor in particular, P2X3, is known to affect this reflexive response.

Heart disease is one of the deadliest killers in the world. Glad to see something developed that maybe able to help it.

 

[Mortimer]

I suffer from sleep apnea, and it is uncomfortable at night, I choke often, have nightmares that Im dying etc....

 

[shockedcanadian]

That is good news. I need something for brain aneurysms, headaches that wake one up multple times in the night.

 

[Harry Dresden]

I suffer from sleep apnea, and it is uncomfortable at night, I choke often, have nightmares that Im dying etc....

go to the doctor have a sleep test and get a C-Pap machine....

 

[luiza]

I suffer from sleep apnea, and it is uncomfortable at night, I choke often, have nightmares that Im dying etc....

Thanks for that news . We can now just wait and hope .

Or , get rid of 100 lbs and there is a good chance that in itself will cure your diarrhea aponea

 

[luiza]

That is good news. I need something for brain aneurysms, headaches that wake one up multple times in the night.

A pillow and a volunteer maybe ?