First thing you need to determine is the type of resume.
Do you have mucho grande experience, but little formal education in the field in which you are applying?
Do you have the opposite...specific education in the field, but little real world experience?
Have you been out of the workforce for a while, and are looking to re-enter?
Do you currently have a job in the field and are exploring possibilities?
Are currently not in the field and looking to break into it, but have work experience elsewhere?
Questions that need to be answered first.