One expert says YES! ***** She adds, however, that they seldom do so, for they rarely feel threatened by other skunks. ***** Then she writes the following that gave me a much needed chuckle: "For example, a female will occasionally spray a male who pesters her too hard for a date (my emphasis), and he slinks away, offended." Source: Marilyn von Savant (notice her last name!), Parade magazine (print edition of May 6, 2018).