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We'll have cancer beat inside a decade.
Poliovirus kills off cancer cells, stops tumor regrowth
Poliovirus kills off cancer cells, stops tumor regrowth
The new research - which is published in the journal Science Translational Medicine - shows how a modified poliovirus enables the body to use its own resources to fight off cancer. The modified virus bears the name of recombinant oncolytic poliovirus (PVS-RIPO).
PVS-RIPO has been in clinical trials since 2011 and preliminary results have offered hope to patients with one of the most aggressive forms of brain tumor: recurrent glioblastoma. So, the researchers set out to investigate more deeply how exactly PVS-RIPO works.
Explaining the rationale behind their research endeavor, Dr. Gromeier says, "Knowing the steps that occur to generate an immune response will enable us to rationally decide whether and what other therapies make sense in combination with poliovirus to improve patient survival."