First Human to Undergo Gene Editing

[JimBowie1958]

It's a Brave New World!

AP Exclusive: US scientists try 1st gene editing in the body

 

[alang1216]

It's a Brave New World!

AP Exclusive: US scientists try 1st gene editing in the body

I've debated with anti-abortion types and have never understood why they think a fertilized egg is a human being with all the legal rights that come with that. It comes down to one question, what makes us human? Gene editing will cloud the issue even more I would think.

 

[JimBowie1958]

I've debated with anti-abortion types and have never understood why they think a fertilized egg is a human being with all the legal rights that come with that. It comes down to one question, what makes us human? Gene editing will cloud the issue even more I would think.

Doing gene editing on a fetus maybe, but on an adult like this person who suffers from a rare genetic disorder?

I am not sure I understand your point.

 

[alang1216]

I've debated with anti-abortion types and have never understood why they think a fertilized egg is a human being with all the legal rights that come with that. It comes down to one question, what makes us human? Gene editing will cloud the issue even more I would think.

Doing gene editing on a fetus maybe, but on an adult like this person who suffers from a rare genetic disorder?

I am not sure I understand your point.

More of a philosophical question I guess.

We can edit the DNA of a fertilized egg (or will soon). To someone who is anti-abortion, does that mean we have killed the original 'human being' and created a totally new one? Did we commit murder and create life at the same time.

 

[Care4all]

500 years from now, we end up looking like this....

And then time travel back to warn us NOT to go down the slippery slope!

 

[JimBowie1958]

I've debated with anti-abortion types and have never understood why they think a fertilized egg is a human being with all the legal rights that come with that. It comes down to one question, what makes us human? Gene editing will cloud the issue even more I would think.

Doing gene editing on a fetus maybe, but on an adult like this person who suffers from a rare genetic disorder?

I am not sure I understand your point.

More of a philosophical question I guess.

We can edit the DNA of a fertilized egg (or will soon). To someone who is anti-abortion, does that mean we have killed the original 'human being' and created a totally new one? Did we commit murder and create life at the same time.

I would say that no, the individual has different DNA but the soul/life essence is still the same.

Every 7 years or so our bodies have filtered out all the old material and is completely new from the old body.

But our souls remain who they are from conception.

At least that is my take on it.

 

[JimBowie1958]

500 years from now, we end up looking like this....

And then time travel back to warn us NOT to go down the slippery slope!

Ahhh, but they look so cute.

Can I have one for a pet?

 

[waltky]

US Scientists Try 1st Gene Editing in the Body...

AP Exclusive: US Scientists Try 1st Gene Editing in the Body
November 15, 2017 — Scientists for the first time have tried editing a gene inside the body in a bold attempt to permanently change a person's DNA to try to cure a disease.

The experiment was done Monday in California on 44-year-old Brian Madeux. Through an IV, he received billions of copies of a corrective gene and a genetic tool to cut his DNA in a precise spot. "It's kind of humbling" to be the first to test this, said Madeux, who has a metabolic disease called Hunter syndrome. "I'm willing to take that risk. Hopefully it will help me and other people." Signs of whether it's working may come in a month; tests will show for sure in three months.

Brian Madeux sits with his girlfriend Marcie Humphrey while waiting to receive the first human gene editing therapy at the UCSF Benioff Children's Hospital in Oakland, Calif.​

If it's successful, it could give a major boost to the fledgling field of gene therapy. Scientists have edited people's genes before, altering cells in the lab that are then returned to patients. There also are gene therapies that don't involve editing DNA. But these methods can only be used for a few types of diseases. Some give results that may not last. Some others supply a new gene like a spare part, but can't control where it inserts in the DNA, possibly causing a new problem like cancer.

This time, the gene tinkering is happening in a precise way inside the body. It's like sending a mini surgeon along to place the new gene in exactly the right location. "We cut your DNA, open it up, insert a gene, stitch it back up. Invisible mending," said Dr. Sandy Macrae, president of Sangamo Therapeutics, the California company testing this for two metabolic diseases and hemophilia. "It becomes part of your DNA and is there for the rest of your life."

That also means there's no going back, no way to erase any mistakes the editing might cause. "You're really toying with Mother Nature" and the risks can't be fully known, but the studies should move forward because these are incurable diseases, said one independent expert, Dr. Eric Topol of the Scripps Translational Science Institute in San Diego.

Protections are in place to help ensure safety, and animal tests were very encouraging, said Dr. Howard Kaufman, a Boston scientist on the National Institutes of Health panel that approved the studies. He said gene editing's promise is too great to ignore. "So far there's been no evidence that this is going to be dangerous," he said. "Now is not the time to get scared."

Woe from head to toe

See also:

FDA Approves First Digital Ingestion Tracking System Med
November 14, 2017 | WASHINGTON — The Food and Drug Administration has approved the first drug in the United States with a digital ingestion tracking system, in an unprecedented move to ensure that patients with mental illness take the medicine prescribed for them.

The drug Abilify MyCite was developed by Otsuka Pharmaceutical Co., Ltd. The drug Abilify was first approved by the FDA in 2002 to treat schizophrenia, and the ingestible sensor, made by Proteus Digital health, was approved for marketing in 2012. The FDA said in a statement Monday that the digitally enhanced medication “works by sending a message from the pill's sensor to a wearable patch.” “Being able to track ingestion of medications prescribed for illness may be useful for some patients,” said Dr. Mitchell Mathis, director of the division of Psychiatry Products in the FDA's Center for Drug Evaluation and Research. “The FDA supports the development and use of new technology in prescription drugs and is committed to working with companies to understand how this technology might benefit patients and prescribers.”

Green-lighting the new medication, however, came with some caveats. Among them, the FDA said it was important to note that Abilify MyCite's labeling asserts “the ability of the product to improve patient compliance with their treatment regimen has not been shown.” “Abilify MyCite should not be used to track drug ingestion in ‘real-time’ or during an emergency,” the statement said, “because detection may be delayed or may not occur.” In a portion of the statement that appeared to address privacy concerns, the FDA said the wearable patch that comes with the medication “transmits the information to a mobile application so that patients can track the ingestion of the medication on their smart phone. Patients can also permit their caregivers and physician to access the information through a web-based portal.”

In a statement issued last May at the time the FDA accepted submission of product for review, Otsuka Pharmaceutical, Ltd. of Toyko and Proteus Digital, of Redwood City, California, said that “with the patient's consent, this information could be shared with their health care professional team and selected family and friends, with the goal of allowing physicians to be more informed in making treatment decisions that are specific to the patient's needs.” The companies said the Proteus Ingestible sensor “activates when it reaches stomach fluids and communicates with the patch.” The FDA said the product is designed for the treatment of schizophrenia, acute treatment of manic and mixed episodes associated with a bipolar disorder and for use as an add-on treatment for depression in adults.”

FDA Approves First Digital Ingestion Tracking System Med

 

[Natural Citizen]

As an informative statement, ''On June 13, 2013, in the case of the Association for Molecular Pathology v. Myriad Genetics, Inc., the Supreme Court of the United States ruled that human genes cannot be patented in the U.S. because DNA is a "product of nature."

But...''The Supreme Court's ruling did allow that DNA manipulated in a lab is eligible to be patented because DNA sequences altered by humans are not found in nature.''

Source: U.S. National Library of Medicine

We're starting to see the use of the term "editing'' more frequently now, whether it be food products or instances such as therein the op.

 

[Likkmee]

Actually it was Noahs grandsons.Beginning with Japheth. The genome was modded to allow a max of 120 years

 

[Natural Citizen]

As an informative statement, ''On June 13, 2013, in the case of the Association for Molecular Pathology v. Myriad Genetics, Inc., the Supreme Court of the United States ruled that human genes cannot be patented in the U.S. because DNA is a "product of nature."

But...''The Supreme Court's ruling did allow that DNA manipulated in a lab is eligible to be patented because DNA sequences altered by humans are not found in nature.''

Source: U.S. National Library of Medicine

Just bumping this as a courtesy.

Reason being is they can't very well create a new law based on a new species until you create a new species under existing law, or Good law.

Association for Molecular Pathology v. Myriad Genetics, Inc. would be considered "Good law" by the way.

This is gonna come up this year. Just wait for it.

Anyway. That is all.

Have a nice day.

 

[fncceo]

have never understood why they think a fertilized egg is a human being with all the legal rights that come with that

Actually, that would be existing legislation.

In most states it is a capital crime, equivalent to murder, to unlawfully terminate a fetus. Feticide is the term.

 

[fncceo]

500 years from now, we end up looking like this....

And then time travel back to warn us NOT to go down the slippery slope!

 

[alang1216]

Actually, that would be existing legislation.

In most states it is a capital crime, equivalent to murder, to unlawfully terminate a fetus. Feticide is the term.

I think that would be anyone BUT the mother.

 

[Natural Citizen]

As an informative statement, ''On June 13, 2013, in the case of the Association for Molecular Pathology v. Myriad Genetics, Inc., the Supreme Court of the United States ruled that human genes cannot be patented in the U.S. because DNA is a "product of nature."

But...''The Supreme Court's ruling did allow that DNA manipulated in a lab is eligible to be patented because DNA sequences altered by humans are not found in nature.''

Source: U.S. National Library of Medicine

We're starting to see the use of the term "editing'' more frequently now, whether it be food products or instances such as therein the op.

Just bumping this as a courtesy.

Reason being is they can't very well create a new law based on a new species until you create a new species under existing law, or Good law.

Association for Molecular Pathology v. Myriad Genetics, Inc. would be considered "Good law" by the way.

This is gonna come up this year. Just wait for it.

Anyway. That is all.

Have a nice day.

Continuing to talk to myself here. Heh heh....

Chile bans discrimination against mutants

“Law No. 21.422 prohibits labor discrimination against mutations or alterations of genetic material, and in turn ‘prohibits demanding any certificate or test to verify that the worker does not have such alterations or mutations in his human genome.'”

The Chilean law recalls the also curious Argentine legislation of last year, which cites the rights of "human persons." Chinda Brandolino has pointed out that this is the legal prelude to a distinction between "human persons" and "transhuman persons". Genetically modified people, says Brandolino, will belong to the owners of the technology and will not have the same rights as "human" people.

The bill - https://expose-news.com/wp-content/uploads/2022/02/Chile-mutant-descrimination-law.pdf



Relevant reading...

SUPREME COURT OF THE UNITED STATES No. 12–398 ASSOCIATION FOR MOLECULAR PATHOLOGY, ET AL., PETITIONERS v. MYRIAD GENETICS, INC., ET AL. ON WRIT OF CERTIORARI TO THE UNITED STATES COURT OF APPEALS FOR THE FEDERAL CIRCUIT [June 13, 2013]

 

[MisterBeale]

Just bumping this as a courtesy.

Reason being is they can't very well create a new law based on a new species until you create a new species under existing law, or Good law.

Association for Molecular Pathology v. Myriad Genetics, Inc. would be considered "Good law" by the way.

This is gonna come up this year. Just wait for it.

Anyway. That is all.

Have a nice day.

I don't know where it is in all the stuff I posted on this forum, but I had postulated, that this, among getting out voters for the DNC, is really what the Dobbs decision is really about.

There is something that the corporatacracy is up to, that will require individual states to pass laws, that Roe would make make women across America able to refuse them.

They needed to get rid of Roe, so that individual states could pass laws for corporate America to protect corporate assets in the brave new world, where between 1 in 4, to 50% of all couples are not able to have children naturally. Anyone that has been paying attention, knows, fertility is plummeting like a rock. "Right to choose" is the least of our problems at this point.



I haven't figured out the specifics yet, but I am pretty sure that there is a lot of money involved, and legal rights for the corporate cabal, and none for the little folks.