Experiments with St. Martin
From Beaumont's Experiments and Observations on the Gastric Juice and the Physiology of Digestion, 1833 (p. 27)
On June 6, 1822, an employee of the American Fur Company on Mackinac Island, named Alexis St. Martin, was accidentally shot in the stomach by a discharge of a musket loaded with a duck shot from close range that injured his ribs and his stomach. Dr. Beaumont treated his wound, but expected St. Martin to die from his injuries.[2][3] Despite this dire prediction, St. Martin survived - but with a hole, or fistula, in his stomach that never fully healed. Unable to continue work for the American Fur Company, he was hired as a handyman by Dr. Beaumont.
By August 1825, Beaumont had been relocated to Fort Niagara in New York, and Alexis St. Martin had come with him. Beaumont recognized that he had in St. Martin the unique opportunity to observe digestive processes. Dr. Beaumont began to perform experiments on digestion using the stomach of St. Martin. Most of the experiments were conducted by tying a piece of food to a string and inserting it through the hole into St. Martin's stomach. Every few hours, Beaumont would remove the food and observe how well it had been digested. Beaumont also extracted a sample of gastric acid from St. Martin's stomach for analysis.
xotoxi posing as William Beaumont.