The only flaw, and it's very minor, is that some images that people post, don't show up because AdBlock blocks it. Then you have to turn it off and reload the page --- if it's worth it to do that. And usually it isn't.
So when I see a post with no content, it means it's a blocked image and I don't bother. I figure if they have a point it can be articulated.
I have another computer that I rarely use for internet and didn't bother to put ABP on. But if I do go online it's torture, especially YouTube. Watch commercials?? Why?