Just a reminder there's folks on these boards with telescopes ... and they know more about these machines than I ...
Temperature differences across a small 6" or 8" mirror would make a huge difference, but this never happens under normal usage ... the larger telescopes are more sensitive, but in the context of gigantic vacuum chambers underneath the speculum, climate control inside the building is easy ... and interplanetary debris is far less a problem than our own atmosphere ...
Stability is a big deal ... especially for our smaller backyard 'scopes ... one idea helps to illustrate the solution ... take an old Chevy 350 V-8 automobile engine and set it up, upside down, with the crankshaft pointed at the North Star ... then pour a couple yards of concrete to hold it in position ... the crankshaft is our polar axis and we can build our equatorial axis easy enough and ... presto ... a one ton German mount that the breeze won't rattle around ... the principle being the heavier the telescope, the less jiggling it'll do when the camera's shutter is open ...
We avoid all this by putting telescope in Earth's orbit ... no wind, no children, no semi-trucks ... and most important, no atmosphere ...
This is the biggest telescope because there's no point building them bigger until we get access to the Tibetan Plateau ... these high mountain-top usually don't even have goat paths to the top ... let alone the Interstate-grade freeway needed to bring materials up ... 400" mirror can't be carried by hand ... drive up San Diego County Road S6 ... yeah ... part of the cost of the Palomar Telescope ...
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So much for late 17th Century technology ... real astronomers use telescopes in pairs or arrays ... the Keck Observatory in Hawai'i is a good example ... TWO of these 400" monsters ... we know the distance between the two very very accurately and that ... er ... well ... frankly I don't know ... here's the Wikipedia article ... I'd rather bail out a septic tank then figure this shit out ... talk about hokay finokay ...
en.wikipedia.org
See where it explains
baseline ... the LIGO experiment had one detector in Louisiana and the other in Washington State ... at scale, we'd want this to be several Neptune-orbit diameters ... anything within the heliosheath ... easy enough to attach EM telescopes and use the same techniques ...
Again, just a reminder there's folks on these boards with telescopes ... and they know more about these machines than I ...