Merck’s New Covid Pill Is a Disaster

excalibur

Diamond Member
Mar 19, 2015
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This drug has no business getting a EUA.


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Molnupiravir Could Drive Escape Mutants

Molnupiravir’s mechanism of action — driving genetic mutations — is in itself problematic, given the already quickly mutating coronavirus spike protein. During Merck’s phase II trial, the SARS-CoV-2 spike protein exhibited 72 structural nucleotide changes, while the spike protein in the placebo group had only nine such changes.

The reality is, some of those changes could make the virus more infective, resistant to vaccines and treatments and unleash escape mutants into the environment.20 FDA panel member James Hildreth, president of Meharry Medical College in Tennessee, voted against authorizing molnupiravir for this reason.

He said, “Even if the probability is very low, 1 in 10,000 or 100,000, that this drug would induce an escape mutant which the vaccines we have do not cover, that would be catastrophic for the whole world.”21 William Haseltine, who founded and chaired the Division of Biochemical Pharmacology at Harvard, raised similar concerns in Forbes, stating:22

“My misgivings are founded on two key concerns. The first is the drug’s potential mutagenicity, and the possibility that its use could lead to birth defects or cancerous tumors. The second is a danger that is far greater and potentially far deadlier: the drug’s potential to supercharge SARS-CoV-2 mutations and unleash a more virulent variant upon the world.”

We’re Heading Toward a ‘World Class Disaster’

Haseltine explained that during prepandemic studies, molnupiravir was tested against pathogenic coronaviruses such as MERS-CoV. Not only were the coronaviruses able to become resistant to the drug, but the viruses continued to survive and replicate even with large numbers of mutations in every gene and protein.

...​


 
This drug has no business getting a EUA.


...​
Molnupiravir Could Drive Escape Mutants
Molnupiravir’s mechanism of action — driving genetic mutations — is in itself problematic, given the already quickly mutating coronavirus spike protein. During Merck’s phase II trial, the SARS-CoV-2 spike protein exhibited 72 structural nucleotide changes, while the spike protein in the placebo group had only nine such changes.​
The reality is, some of those changes could make the virus more infective, resistant to vaccines and treatments and unleash escape mutants into the environment.20 FDA panel member James Hildreth, president of Meharry Medical College in Tennessee, voted against authorizing molnupiravir for this reason.​
He said, “Even if the probability is very low, 1 in 10,000 or 100,000, that this drug would induce an escape mutant which the vaccines we have do not cover, that would be catastrophic for the whole world.”21 William Haseltine, who founded and chaired the Division of Biochemical Pharmacology at Harvard, raised similar concerns in Forbes, stating:22​
“My misgivings are founded on two key concerns. The first is the drug’s potential mutagenicity, and the possibility that its use could lead to birth defects or cancerous tumors. The second is a danger that is far greater and potentially far deadlier: the drug’s potential to supercharge SARS-CoV-2 mutations and unleash a more virulent variant upon the world.”
We’re Heading Toward a ‘World Class Disaster’
Haseltine explained that during prepandemic studies, molnupiravir was tested against pathogenic coronaviruses such as MERS-CoV. Not only were the coronaviruses able to become resistant to the drug, but the viruses continued to survive and replicate even with large numbers of mutations in every gene and protein.​
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Of course immune escape did not worry them at all when it came to the vaccines
 
Of course, everybody should be vaccinated.

Everyone I know at work who is getting covid now is double vaccinated. Some are boosted.

Here I am. Unvaxxed. No covid yet.

OH look Penelope doesn't like this. She "disagrees" with it. Which part? The part about double vaxxed getting all the infections? The part about me being unvaxxed and yet not having caught covid yet?

Penny doesn't like it when people don't obey her god, Big Daddy Govco. We know this
 
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Fauci and Gates don't give a shit about conquering COVID. In fact, they don't want to control it. They just want to sell vaccines that don't work for as long as they can get away with it.
 
Too late. It's already been approved. One can only hope that no one ever uses this pill because the pfizer one is way more effective. Only high risk patients are allowed to take it, which doesn't seem to make sense because if they're high risk, wouldn't it make sense to give them a pill with 90% efficacy as opposed to 30%? What would be the point of giving a high risk covid patient a less effective pill?
 
This drug has no business getting a EUA.


...​
Molnupiravir Could Drive Escape Mutants
Molnupiravir’s mechanism of action — driving genetic mutations — is in itself problematic, given the already quickly mutating coronavirus spike protein. During Merck’s phase II trial, the SARS-CoV-2 spike protein exhibited 72 structural nucleotide changes, while the spike protein in the placebo group had only nine such changes.​
The reality is, some of those changes could make the virus more infective, resistant to vaccines and treatments and unleash escape mutants into the environment.20 FDA panel member James Hildreth, president of Meharry Medical College in Tennessee, voted against authorizing molnupiravir for this reason.​
He said, “Even if the probability is very low, 1 in 10,000 or 100,000, that this drug would induce an escape mutant which the vaccines we have do not cover, that would be catastrophic for the whole world.”21 William Haseltine, who founded and chaired the Division of Biochemical Pharmacology at Harvard, raised similar concerns in Forbes, stating:22​
“My misgivings are founded on two key concerns. The first is the drug’s potential mutagenicity, and the possibility that its use could lead to birth defects or cancerous tumors. The second is a danger that is far greater and potentially far deadlier: the drug’s potential to supercharge SARS-CoV-2 mutations and unleash a more virulent variant upon the world.”
We’re Heading Toward a ‘World Class Disaster’
Haseltine explained that during prepandemic studies, molnupiravir was tested against pathogenic coronaviruses such as MERS-CoV. Not only were the coronaviruses able to become resistant to the drug, but the viruses continued to survive and replicate even with large numbers of mutations in every gene and protein.​
...​


We don't think the vaccine uses the spike part of the virus that contains the increased risk for breast cancer, so the pill will be a good way to find out about mutations. The pill's chemistry started in Siberia, 1973.
 
Too late. It's already been approved. One can only hope that no one ever uses this pill because the pfizer one is way more effective. Only high risk patients are allowed to take it, which doesn't seem to make sense because if they're high risk, wouldn't it make sense to give them a pill with 90% efficacy as opposed to 30%? What would be the point of giving a high risk covid patient a less effective pill?
Pfizer's pill is a choice, but only after effective prophylaxis (hcq/ivm) or a real SARS-CoV-2 vaccine (India's Covaxin) have been taken away from the prisoners.
 
This drug has no business getting a EUA.


...​
Molnupiravir Could Drive Escape Mutants
Molnupiravir’s mechanism of action — driving genetic mutations — is in itself problematic, given the already quickly mutating coronavirus spike protein. During Merck’s phase II trial, the SARS-CoV-2 spike protein exhibited 72 structural nucleotide changes, while the spike protein in the placebo group had only nine such changes.​
The reality is, some of those changes could make the virus more infective, resistant to vaccines and treatments and unleash escape mutants into the environment.20 FDA panel member James Hildreth, president of Meharry Medical College in Tennessee, voted against authorizing molnupiravir for this reason.​
He said, “Even if the probability is very low, 1 in 10,000 or 100,000, that this drug would induce an escape mutant which the vaccines we have do not cover, that would be catastrophic for the whole world.”21 William Haseltine, who founded and chaired the Division of Biochemical Pharmacology at Harvard, raised similar concerns in Forbes, stating:22​
“My misgivings are founded on two key concerns. The first is the drug’s potential mutagenicity, and the possibility that its use could lead to birth defects or cancerous tumors. The second is a danger that is far greater and potentially far deadlier: the drug’s potential to supercharge SARS-CoV-2 mutations and unleash a more virulent variant upon the world.”
We’re Heading Toward a ‘World Class Disaster’
Haseltine explained that during prepandemic studies, molnupiravir was tested against pathogenic coronaviruses such as MERS-CoV. Not only were the coronaviruses able to become resistant to the drug, but the viruses continued to survive and replicate even with large numbers of mutations in every gene and protein.​
...​


I don't put in any stock from a right-wing rag.
 
Pfizer's pill is a choice, but only after effective prophylaxis (hcq/ivm) or a real SARS-CoV-2 vaccine (India's Covaxin) have been taken away from the prisoners.

:cuckoo:


I don't put in any stock from a right-wing rag.

You shouldn't. Only idiots and sheep read that stuff. Unfortunately, the same thing is being said in the MSM as well.
 

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