Regina Golan-Gerstl, Ph.D., a postdoctoral fellow at the Hebrew University Hadassah Medical School, has successfully identified a genetic protein which is involved in the development of the most common and aggressive type of brain cancer found in adults called glioblastoma.
For the 22,000 American citizens who are diagnosed each year with brain cancer, these never before known molecular aspects can provide new diagnosis and treatment options for patients.
Golan-Gerstl and her team of biochemists supported by the Israel Cancer Research Fund (ICRF) discovered a splicing factor hnRNP A2/B1, a protein gene found in humans, which was detected to have higher than normal levels found in glioblastoma samples.
A study was conducted on laboratory mice to see what would happen when injected with gliobastoma cells. Shortly after being injected, mice quickly developed large tumors, but when researchers used a biologic technique ("knockdown") to reduce hnRNP A2/B1 before injection, the mice developed only small tumors or no tumors at all.
Israel Discovers New Therapy For Brain Cancer - Technology, Science, Health - News - Israel National News
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Well done!
For the 22,000 American citizens who are diagnosed each year with brain cancer, these never before known molecular aspects can provide new diagnosis and treatment options for patients.
Golan-Gerstl and her team of biochemists supported by the Israel Cancer Research Fund (ICRF) discovered a splicing factor hnRNP A2/B1, a protein gene found in humans, which was detected to have higher than normal levels found in glioblastoma samples.
A study was conducted on laboratory mice to see what would happen when injected with gliobastoma cells. Shortly after being injected, mice quickly developed large tumors, but when researchers used a biologic technique ("knockdown") to reduce hnRNP A2/B1 before injection, the mice developed only small tumors or no tumors at all.
Israel Discovers New Therapy For Brain Cancer - Technology, Science, Health - News - Israel National News
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Well done!
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