Practically nothing about physics is settled until a workable grand unified theory that ties together classical physics and quantum physics is formulated. Maybe in a few hundred more years?
Personally I don't believe science can/could ever be settled. Science is an everlasting search for what's next before the next arrives
just my view

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Science is a process and it continues on indefinitely. What we 'know' today will be very different from what we 'know' tomorrow.
Indeed the study of the "things made" will continue forever (Romans 1:20). And we will never know it all:
In Ecclesiastes 3:11 the Hebrew word "olam " actually means hidden or concealed time but is usually translated "everlasting" (or "eternity,' etc.).
See:
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The context shows that revealing hidden things *by scientific study" will continue forever:
Ecclesiastes 3:11
He has made everything beautiful
* in its time.
+ He has even put eternity in their heart; yet mankind will never find out the work that the true God has made from start to finish.
That's one of the reasons I love science - we will always have the joy of discovery! Eternal life on a paradise earth (Psalms 37:29; Isaiah 11:7-9) will never be boring!
Concerning relativity (Einstein's theory):
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Excerpts:
"Einstein’s special theory of relativity, published in June 1905, disagreed with a fundamental belief of scientists such as Isaac Newton—that the measurement of time is a constant throughout the universe....
However, when approaching the speed of light, not only does time slow down significantly but objects also become smaller and their mass increases. Einstein’s theory maintained that the speed of light, not time, is constant across the universe.....
Clocks aboard satellites of the Global Positioning System (GPS) do not tick at the same speed as clocks on earth. Without correcting for this effect of relativity, the GPS signal would be rendered useless."
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"Carl B. Boyer observes: “Within a raindrop the interaction of light energy with matter is so intimate that one is led directly to quantum mechanics and the theory of relativity. . . . Although much is known about the production of the rainbow, little has been learned about its perception.”—
The Rainbow, From Myth to Mathematics, 1959, pp. 320, 321."
Concerning the cosmological constant and relativity and expansion of the universe (Isaiah 40:22):
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"Albert Einstein’s general theory of relativity, published in 1916, implied that the universe is either expanding or contracting. Yet, the idea was totally contrary to the then accepted view that the universe is static, which Einstein also believed at the time. So he introduced into his calculations what he called a “cosmological constant.” This adjustment was made to try to harmonize his theory with the accepted belief that the universe is static and unchanging.
However, evidence that accumulated in the 1920’s caused Einstein to call the adjustment he had made to the relativity theory his ‘greatest blunder.’ The installation of the huge 100-inch
[254 cm] telescope on Mount Wilson in California made possible the acquisition of such evidence. The observations made with the use of that telescope during the 1920’s proved that the universe is expanding!"
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"The truth is, educated people today are less prepared than was David Hume to insist that the familiar laws of nature hold true everywhere and at all times. Scientists are willing to speculate on whether, instead of the familiar three dimensions of length, breadth, and height, there may be many additional dimensions in the universe.2 They theorize on the existence of black holes, huge stars that collapse in on themselves until their density is virtually infinite. In their vicinity the fabric of space is said to be so distorted that time itself stands still.3 Scientists have even debated whether, under certain conditions, time would run backward instead of forward!4
8 Stephen W. Hawking, Lucasian Professor of Mathematics at Cambridge University, when discussing how the universe began, said: “In the classical theory of general relativity . . . the beginning of the universe has to be a singularity of infinite density and space-time curvature. Under such conditions, all the known laws of physics would break down.”5"
references 2-5 -
2.
Discover, November 1986, p. 34.
3.
Einstein’s Universe, by Nigel Calder, 1979, p. 40.
4.
Discover, February 1987, p. 67.
5.
Discover, February 1987, p. 70.