Read the link, dimbfuck. A mutation is not having an extra chromosome. That is a disorder, a syndrome, like Downs.
You people need to learn the fucking biology.
Go and have a nice cup of tea and a lie down, dear. You are clearly overwrought
Hey, dumb bitch #2, tell me where in here it says that having an extra chromosome, or missing one, is a "genetic mutation? It doesn't because, it isn't. You lose.
What is a gene mutation and how do mutations occur?
A gene mutation is a permanent alteration in the DNA sequence that makes up a gene, such that the sequence differs from what is found in most people. Mutations range in size; they can affect anywhere from a single DNA building block (base pair) to a large segment of a chromosome that includes multiple genes.
Gene mutations can be classified in two major ways:
- Hereditary mutations are inherited from a parent and are present throughout a person’s life in virtually every cell in the body. These mutations are also called germline mutations because they are present in the parent’s egg or sperm cells, which are also called germ cells. When an egg and a sperm cell unite, the resulting fertilized egg cell receives DNA from both parents. If this DNA has a mutation, the child that grows from the fertilized egg will have the mutation in each of his or her cells.
- Acquired (or somatic) mutations occur at some time during a person’s life and are present only in certain cells, not in every cell in the body. These changes can be caused by environmental factors such as ultraviolet radiation from the sun, or can occur if a mistake is made as DNA copies itself during cell division. Acquired mutations in somatic cells (cells other than sperm and egg cells) cannot be passed on to the next generation.
What is a gene mutation and how do mutations occur?
That describes Down's syndrome. Lol.
No, it doesn't not you stupid ****.
That discusses a single pair or a mutation across several genes on one C H R O M O S O M E. It doesn't say anything about having one fewer or one too many.
Down's Syndrome is a Genetic Disorder, a T R I S O M Y, not a mutation.
Learn the biology.
Sorry, it is a genetic mutation and has nothing to do with being a transgender.
Trisomy 21
Trisomy 21 (also known by the
karyotype 47,XX,+21 for females and 47,XY,+21 for males)
[58] is caused by a failure of the 21st chromosome to separate during egg or sperm development.
[54] As a result, a sperm or egg cell is produced with an extra copy of chromosome 21; this cell thus has 24 chromosomes. When combined with a normal cell from the other parent, the baby has 47 chromosomes, with three copies of chromosome 21.
[1][54] About 88% of cases of trisomy 21 result from nonseparation of the chromosomes in the mother, 8% from nonseparation in the father, and 3% after the egg and sperm have merged.
[59]
Translocation
The extra chromosome 21 material may also occur due to a
Robertsonian translocation in 2–4% cases.
[53][60] In this situation, the long arm of chromosome 21 is attached to another chromosome, often
chromosome 14.
[61] In a male affected with Down syndrome, it results in a karyotype of 46XY,t(14q21q).
[61][62] This may be a new mutation or previously present in one of the parents.
[63] The parent with such a translocation is usually normal physically and mentally;
[61]however, during production of egg or sperm cells, a higher chance of creating reproductive cells with extra chromosome 21 material exists.
[60] This results in a 15% chance of having a child with Down syndrome when the mother is affected and a less than 5% probability if the father is affected.
[63] The probability of this type of Down syndrome is not related to the mother's age.
[61] Some children without Down syndrome may inherit the translocation and have a higher probability of having children of their own with Down syndrome.
[61] In this case it is sometimes known as familial Down syndrome.
[64]
