Studies show gene maps can spot disease

Discussion in 'Current Events' started by Chris, Mar 11, 2010.

  1. Chris
    Offline

    Chris Gold Member

    Joined:
    May 30, 2008
    Messages:
    23,154
    Thanks Received:
    1,958
    Trophy Points:
    205
    Location:
    Virginia
    Ratings:
    +2,089
    Reuters) - Two studies published on Wednesday show it is possible to sequence the entire gene maps of families with inherited diseases and pinpoint the offending bit of DNA.

    The studies, which would not have been possible a year or two ago, are the first real delivery of the promised transformation of medical science from the Human Genome Project's mapping of the human genetic code.

    One was also made possible by some of the $5 billion that U.S. President Barack Obama directed to the National Institutes of Health in September from the $787 billion economic stimulus package.

    And in that study, the genetic researcher was himself one of the patients.

    Dr. James Lupski of the Baylor College of Medicine in Houston has a recessive genetic disease called Charcot-Marie-Tooth syndrome. It affects the nerves stretching from the spinal cord to the arms, legs and feet.

    Lupski has been experimenting on himself and his own family for years.

    We tried every other method for 25 years to find out which mutation was important," he said in a telephone interview.

    "With this methodology we were able to do it. This is the first time whole genome sequencing has applied to actually find the cause of a disease."

    Personal study shows gene maps can spot disease | Reuters
     
  2. Dr Gregg
    Offline

    Dr Gregg BANNED

    Joined:
    Jan 28, 2010
    Messages:
    2,901
    Thanks Received:
    198
    Trophy Points:
    0
    Ratings:
    +200
    Sequencing of the human genome is going to lead to huge advances in medicine. I can see in the next decade a new field of pharmacogenomics where they can tailor treatments to your genetics, to maximize treatment and reduce side effects of particular drugs.

    it's pretty amazing, I know that many cancer researchers at my institute can analyze tumors and find specific nucleotide changes in genes to determine what genes,a nd what mutations occur in certain forms of cancer. Can totally help in targeting tumors with treatment that won't effect healthy cells, which is what makes most cancer treatments so horrible to go through.

    It's scary how much the technology has advanced in the 11 years I"ve been doing research, and how much more it does nearly every year.
     
  3. uscitizen
    Offline

    uscitizen Senior Member

    Joined:
    May 6, 2007
    Messages:
    45,941
    Thanks Received:
    4,791
    Trophy Points:
    48
    Location:
    My Shack
    Ratings:
    +4,807
    Why is it called "Sequencing of the human genome"
    It is really understanding the genome and how their sequencing impacts us?
     

Share This Page